Autoamputation of Dermatofibrosarcoma Protuberans: A Novel and Rare Presentation of a Familiar Entity

International Journal of Surgical Pathology
Judith Jebastin ThangaiahKyle Perry

Abstract

Dermatofibrosarcoma protuberans (DFSP) is categorized as a fibrohistiocytic tumor of intermediate malignant potential. It has significant risk for local recurrence and, less commonly, local or distant metastasis. Initially, these tumors typically arise as a firm plaque on the skin that slowly progresses to a nodular and protuberant dermal lesion. DFSP can also exhibit ulceration, hemorrhage, and accelerated growth, but autoamputation has not been described in the English literature. In this article, we report a case of an asymptomatic classical DFSP on the upper back in which the protuberant portion spontaneously autoamputated. In this case, the residual lesion was treated with Mohs micrographic surgery. The presentation, features, and implications of this interesting mode of presentation are discussed.

References

Mar 1, 1992·CA: a Cancer Journal for Clinicians·W B Laskin
Jul 1, 1974·Plastic and Reconstructive Surgery·S S ManalanS D Theogaraj
Jul 1, 1962·Cancer·H B TAYLOR, E B HELWIG
Jun 29, 2010·Pediatric Blood & Cancer·Saskia L M GooskensMarry M van den Heuvel-Eibrink
Sep 20, 2011·Gut and Liver·Hye Kyong JeongYoung Eun Joo
Feb 1, 2012·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Benjamin BoguckiEva A Hurst
Jan 15, 2015·Journal of the American Academy of Dermatology·Paul M HoeslyJulia S Lehman
Jun 13, 2016·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Keiko HayakawaNoriko Motoi
Aug 19, 2016·World Journal of Surgical Oncology·Keun Ho LeeEun Kyung Park

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