PMID: 8949441Sep 1, 1996Paper

Autoantibodies to bullous pemphigoid and epidermolysis bullosa acquisita antigens in an infant

The British Journal of Dermatology
Y KawachiF Otsuka

Abstract

We describe a 1-year-old boy with multiple tense blisters on the skin, who showed circulating autoantibodies directed to both bullous pemphigoid and epidermolysis bullosa acquisita antigens. The patient's serum IgG antibodies bound to the 290-kDa epidermolysis bullosa acquisita antigen with immunoblot analysis of human dermal extracts. Immunoblot analysis also demonstrated that the patient's serum autoantibodies were reactive with recombinant NC16a domain of the 180-kDa bullous pemphigoid antigen. This study confirmed the presence of circulating autoantibodies directed to both bullous pemphigoid antigen and epidermolysis bullosa acquisita antigen.

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Citations

Feb 15, 2001·Clinics in Dermatology·S Brenner, J Mashiah
Mar 15, 2011·Annales de dermatologie et de vénéréologie·C Le Roux-Villet, C Prost-Squarcioni
Dec 20, 2005·The Journal of Dermatology·Sei-Ichiro MotegiOsamu Ishikawa
Oct 23, 2012·The Australasian Journal of Dermatology·Baoqi YangFuren Zhang
Jul 10, 2004·Journal of the American Academy of Dermatology·Janet A FairleyMong-Shang Lin
Oct 20, 2007·Journal of the American Academy of Dermatology·Orith Waisbourd-ZinmanAlex Zvulunov
Nov 23, 2017·The British Journal of Dermatology·C Prost-SquarcioniD F Murrell
Aug 10, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·Masumi OsawaTakashi Hashimoto

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