Autocidal control of ticks by silencing of a single gene by RNA interference

Biochemical and Biophysical Research Communications
José de la FuenteK M Kocan

Abstract

Ticks impact human and animal health worldwide and new control methods are needed to circumvent drawbacks of tick control by acaricide application including selection of drug resistant ticks and environmental pollution. Using RNA interference we silenced the expression of a single gene, subolesin, and produced ticks with diminished reproductive performance and prevented successful mating and production of viable offspring. We propose a sterile acarine technique (SAT) for reduction of tick populations by release of subolesin-silenced ticks. Conservation of subolesin among tick species suggests that SAT may be useful for control of many medically and economically important tick species.

References

Jun 1, 1972·Parasitology·R E PurnellM A Ledger
Aug 1, 1982·Veterinary Parasitology·W N Beesley
Apr 12, 2001·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·P Parola, D Raoult
Apr 13, 2005·Parasitology Research·José de la FuenteKatherine M Kocan
Jun 9, 2005·Parasitology·P Willadsen
Jul 12, 2005·Vaccine·Consuelo AlmazánJosé de la Fuente

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Citations

Aug 5, 2008·BMC Genomics·José de la FuenteKatherine M Kocan
Feb 23, 2010·BMC Immunology·Zorica ZivkovicJosé de la Fuente
Apr 10, 2010·Parasites & Vectors·Adalberto A Pérez de LeónUNKNOWN Group for Emerging Babesioses and One Health Research and Development in the U.S
Dec 7, 2011·PloS One·Kyaw Min AungKozo Fujisaki
Feb 10, 2011·Journal of Visualized Experiments : JoVE·Katherine M KocanJosé de la Fuente
Feb 21, 2009·Parasitology Research·Mario CanalesJosé de la Fuente
Jan 8, 2013·Vaccine·Juan A Moreno-CidUNKNOWN SUB/AKR Vaccine Study Group
Dec 2, 2008·Developmental and Comparative Immunology·Ruth C GalindoJosé de la Fuente
Jul 28, 2007·Trends in Parasitology·José de la FuenteEdmour F Blouin
Jul 28, 2007·Trends in Parasitology·Kirsty JensenElizabeth J Glass
Jun 15, 2007·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·O A E Sparagano, C J De Luna
Jan 6, 2009·Annals of the New York Academy of Sciences·Edmour F BlouinKatherine M Kocan
Jan 6, 2009·Annals of the New York Academy of Sciences·José de la FuenteKatherine M Kocan
Jul 3, 2010·Vaccine·Carlos R PrudencioJosé de la Fuente
Apr 12, 2016·Ticks and Tick-borne Diseases·Remil Linggatong GalayTetsuya Tanaka
Jan 4, 2015·Veterinary Parasitology·José de la FuenteRuth C Galindo
Oct 13, 2009·Veterinary Parasitology·José de la FuenteAtilio J Mangold
Mar 20, 2012·Veterinary Parasitology·Timea KissMarina Spînu
Dec 6, 2014·Gene·Chiara ManfrinAlberto Pallavicini
Jul 28, 2017·Insect Science·Zachary Y HuangXianbing Xie

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