AutoCPAP initiation at home: optimal trial duration and cost-effectiveness

Sleep Medicine
Adel BachourPaula Maasilta


The duration of automatic computer-controlled continuous positive airway pressure device (autoCPAP) initiation at home varies largely between sleep centers. Our objectives were to evaluate the cost-effectiveness and to find the optimal trial duration. Of the 206 consecutive CPAP-naive patients with obstructive sleep apnea syndrome, who were referred to our hospital, 166 received autoCPAP for a 5-day trial at home. Of the 166 patients, 89 (15 women) showed a successful 5-day autoCPAP trial (normalized oximetry and mask-on time exceeding 4 h/day for at least 4 days). For the first trial day, 88 (53%) patients had normalized oximetry and a mask-on time exceeding 4 h. A 1-day autoCPAP trial EUR 668 was less cost-effective than a 5-day trial EUR 653, with no differences in values of efficient CPAP pressure or residual apnea-hypopnea index (AHI). The systematic requirement of oximetry monitoring raised the cost considerably from EUR 481 to EUR 668. In selected patients with obstructive sleep apnea, the optimal duration for initiating CPAP therapy at home by autoCPAP is 5 days. Although a 1-day trial was sufficient to determine the CPAP pressure requirement, it was not cost-effective and had a high rate of failure.


Jun 1, 1990·The American Review of Respiratory Disease·M J WasickoN H Edelman
Apr 1, 1993·The American Review of Respiratory Disease·N B KribbsD F Dinges
Jan 1, 1996·American Journal of Respiratory and Critical Care Medicine·J C MeuriceF Sériès
Sep 1, 1996·American Journal of Respiratory and Critical Care Medicine·H TeschlerN Konietzko
Dec 1, 1996·American Journal of Respiratory and Critical Care Medicine·P LloberesR Rodriguez-Roisin
Jun 10, 2000·Journal of Sleep Research·A T Whittle, Neil J Douglas
Sep 16, 2000·American Journal of Respiratory and Critical Care Medicine·F PortierJ F Muir
Oct 31, 2002·American Journal of Respiratory and Critical Care Medicine·Clifford A MassieNeil J Douglas
Feb 20, 2004·Respiratory Medicine·J R StradlingD M Smith
Oct 16, 2004·American Journal of Respiratory and Critical Care Medicine·William A WhitelawW Ward Flemons
Mar 1, 2005·Respiratory Medicine·Oreste MarroneGiovanni Bonsignore


Jul 3, 2013·Sleep & Breathing = Schlaf & Atmung·Hanna-Riikka KreiviAdel Bachour
Jul 6, 2012·Sleep & Breathing = Schlaf & Atmung·Adel BachourPaula Maasilta
Dec 15, 2015·Sleep & Breathing = Schlaf & Atmung·Adel BachourPaula Maasilta
Apr 9, 2016·Sleep & Breathing = Schlaf & Atmung·Paula KauppiAdel Bachour
Apr 1, 2015·Revue des maladies respiratoires·E AntoneJ C Meurice
Apr 23, 2013·Respirology : Official Journal of the Asian Pacific Society of Respirology·Mario Francesco DamianiOnofrio Resta

Related Concepts

Cost Effectiveness
Home Care of Patient
Severity of Illness Index
Body Mass Index Procedure
Sleep Apnea, Obstructive
Nasal Continuous Positive Airway Pressure

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