Autofluorescence and light transmission in the aging crystalline lens

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
J R OcchipintiN L Burstein

Abstract

We quantitated blue-green light transmission and autofluorescence of the human crystalline lens in vivo, using an automated scanning fluorophotometer (Fluorotron) coupled with a lens system designed for high resolution of the ocular anterior segment. Lenses were scanned through the dilated pupil along the optical axis, generating a fluorescence profile consisting of anterior and posterior juxtacortical peaks and a central plateau. Fluorescence increased linearly with increasing age. We calculated percent transmission of excitation (410-500 nm) and emission (510-670 nm) as the ratio of posterior to anterior juxtacortical peaks. Light transmission decreased as a parabolic function of age and was correlated with both fluorescence increase and observed lens brunescence.

Citations

Jan 1, 1988·International Ophthalmology·N A BrownJ M Sparrow
Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M LarsenH Lund-Andersen
Jan 5, 2002·Ophthalmology·Carlos LazaroJulian Garcia-Sanchez
Feb 13, 2003·Ophthalmology·Richard F Spaide
Oct 6, 1999·Journal of Diabetes and Its Complications·A Di BenedettoD Cucinotta
Apr 1, 1989·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·R P HemengerM A Mosier
Jan 1, 1992·The British Journal of Ophthalmology·J M SparrowH A Neil
Jul 1, 1995·The British Journal of Ophthalmology·E V KuppensC C Sterk
Oct 1, 1990·Documenta Ophthalmologica. Advances in Ophthalmology·H J Van den BromL J Blanksma
Mar 16, 2007·Experimental Eye Research·Xianmin LuoSteven Bassnett
May 31, 2014·Journal of Diabetes Science and Technology·Frederick CahnShardendu Mishra
Sep 22, 1996·Proceedings. Biological Sciences·R A Weale
Jan 1, 1994·International Ophthalmology·S FantaguzziR Brancato
Feb 20, 1998·Acta Ophthalmologica Scandinavica·S SiikH Nieminen
Apr 1, 1991·Acta Ophthalmologica·S SiikH Nieminen

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