Autofluorescence imaging of cystoid macular edema in diabetic retinopathy

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Alfredo PeceRosario Brancato

Abstract

Our purpose was to assess fundus autofluorescence (FAF) images in patients with diabetic retinopathy and cystoid macular edema (CME) and their correlation with fluorescein angiography (FA) and optical coherence tomography (OCT) findings. Sixty-eight eyes of 34 consecutive patients with diabetic retinopathy were examined with autofluorescence imaging using a confocal scanning laser ophthalmoscope, FA and OCT. The eyes were divided into 2 groups, group 1 with CME and group 2 without. In the 44 eyes of group 1 (65% of the series), we identified 3 patterns of FAF: (1) multicystic increased FA (57%), (2) a single cyst of increased FAF (16%), (3) combined single- and multicystic increased FAF (27%). FA and OCT gave a positive correlation between cystic increased FAF and CME (r = 0.95; p = 0.001). Visual acuity loss was not correlated with the size of the cystic area (p = 0.83), but it was related to significant macular thickening (p = 0.007). Confocal scanning laser ophthalmoscopy can selectively visualize autofluorescent, multilobulated spaces in eyes with diabetic CME. Even if OCT remains preferable for evaluating macular thickening and cysts, FAF might be another useful easy test to rapidly distinguish this entity noninvasively an...Continue Reading

Citations

Dec 5, 2012·Journal of Ophthalmology·Tetsuju SekiryuYukinori Sugano
Mar 10, 2016·Indian Journal of Ophthalmology·Colin Siang Hui TanSrinivas R Sadda
Feb 4, 2016·Clinical & Experimental Ophthalmology·Emily Dawn ColeNadia K Waheed
Jul 4, 2015·Indian Journal of Ophthalmology·Andrea GabaiPaolo Lanzetta
May 8, 2016·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Edoardo Midena, Silvia Bini
Oct 23, 2016·Journal français d'ophtalmologie·W ZbibaA Daldoul
Jan 30, 2018·Asia-Pacific Journal of Ophthalmology·Dhariana Acón, Lihteh Wu
Nov 22, 2015·Journal of Biomedical Optics·Asael PapourWarren Grundfest
Apr 12, 2012·Acta Ophthalmologica·Stela VujosevicEdoardo Midena
Jun 17, 2019·Acta Diabetologica·Maria Vittoria CicinelliFrancesco Bandello
May 6, 2016·Journal of Diabetes·Ana M Calvo-MarotoAlejandro Cerviño
Sep 15, 2020·Therapeutic Advances in Ophthalmology·Sergio E Hernández Da MotaRaul Vélez-Montoya
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May 24, 2012·International Ophthalmology·Edoardo Midena, Stela Vujosevic
Dec 31, 2020·Journal of Clinical Medicine·Stela VujosevicStefano De Cillà

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