Autofluorescence method to measure macular pigment optical densities fluorometry and autofluorescence imaging

Archives of Biochemistry and Biophysics
François Delori

Abstract

Non-invasive measurement of the optical density of the human macular pigment by the autofluorescence method takes advantage of the fluorescence of lipofuscin in the human retinal pigment epithelium. Measuring the intensity of fluorescence above 550 nm, where macular pigment has essentially zero absorption, and stimulating the fluorescence with two wavelengths, one well absorbed by macular pigment and the other minimally absorbed by macular pigment, provides a single-pass measurement of the macular pigment optical density. The method is implemented either by fluorometry of lipofuscin to yield the optical density of the macular pigment in a 2 degrees diameter central area, or by autofluorescence imaging to yield a high-resolution map of the macular pigment distribution.

References

Jul 1, 1997·Experimental Eye Research·J T LandrumK E Sprague

❮ Previous
Next ❯

Citations

Apr 28, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·M TrieschmannD Pauleikhoff
Jan 12, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Olivia HowellsHannah Bartlett
Aug 19, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Yuzuru SasamotoKohji Nishida
May 3, 2005·Experimental Eye Research·Janet R Sparrow, Mike Boulton
Feb 25, 2009·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Rob L P van der VeenIan J Murray
Sep 4, 2008·Photochemistry and Photobiology·Prasun MukherjeeJacob W Petrich
Oct 28, 2011·Journal of Biomedical Optics·Amani A FawziR Theodore Smith
Apr 14, 2007·The British Journal of Ophthalmology·Daniel LavinskyRubens Belfort
Apr 23, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Bogdana KomarJens Dawczynski
Jan 11, 2007·Journal of Biomedical Optics·Jan van de KraatsDirk van Norren
Dec 2, 2015·Journal of Agricultural and Food Chemistry·Ujjal BhattacharjeeJacob W Petrich
Jul 22, 2011·Optometry : Journal of the American Optometric Association·William J DentonWilliam J McGill
Feb 24, 2009·Experimental Eye Research·Peter Charbel IssaTos T J M Berendschot
Apr 26, 2008·Optometry : Journal of the American Optometric Association·Ivan Y-F Leung
Dec 22, 2007·Experimental Eye Research·T TheelenB J Klevering
Feb 8, 2013·Acta Ophthalmologica·Thomas TheelenMichèl A A P Willemsen
Dec 29, 2005·Experimental Eye Research·S H Melissa LiewChristopher J Hammond
Jul 20, 2018·Investigative Ophthalmology & Visual Science·Akira ObanaPaul S Bernstein
Mar 17, 2006·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·François C DeloriGiovanni Staurenghi
Sep 21, 2006·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Mohsen SharifzadehWerner Gellermann
Nov 26, 2016·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Christopher M Putnam
Apr 25, 2019·Scientific Reports·Lijuan ChenJanet R Sparrow
May 6, 2019·Investigative Ophthalmology & Visual Science·Gregor Sebastian ReiterAndreas Pollreisz
May 16, 2019·Annual Review of Nutrition·Lydia SauerPaul S Bernstein
Sep 17, 2014·Journal of Biomedical Optics·Mohsen SharifzadehWerner Gellermann
Oct 20, 2018·Ophthalmic Surgery, Lasers & Imaging Retina·Jorge Orellana-RiosR Theodore Smith
Aug 31, 2019·Biomedical Optics Express·Dimitrios ChristarasPablo Artal
May 15, 2020·Optics Express·Francisco ÁvilaLaura Remón
Dec 24, 2019·Translational Vision Science & Technology·Marina Green-GomezJohn M Nolan

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
M TrieschmannD Pauleikhoff
Archives of Biochemistry and Biophysics
Richard A Bone, John T Landrum
Archives of Biochemistry and Biophysics
J D Moreland
© 2021 Meta ULC. All rights reserved