PMID: 6991979May 15, 1980Paper

Autograft of pancreatic tissue in the spleen of pancreatectomized dogs

Minerva chirurgica
B MicaliV Fabiano

Abstract

The intrasplenic autotransplant of pancreatic fragments in dogs subjected to total pancreatectomy can prevent diabetes as it maintains normoglycaemic condition and a normal insulinaemic response to i.v. infusion of glucose. By adopting a pancreatic tissue preparation technique which provides for a very short collagenasis digestion time (4 minutes), B cells took and normal glucidic metabolism was maintained.

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