Autoimmune channelopathies: John Newsom-Davis's work and legacy. A summary of the Newsom-Davis Memorial Lecture 2008

Journal of Neuroimmunology
Angela Vincent

Abstract

John Newsom-Davis was a key figure in the field of neuroimmunology and combined many outstanding personal qualities with considerable clinical and scientific expertise. His first report of plasma exchange in myasthenia in the late 1970s demonstrated its use both as a treatment and as an experimental tool to establish the pathogenic role of antibodies in neurological disorders. Subsequent investigations into the Lambert Eaton myasthenic syndrome and acquired neuromyotonia showed that these were caused by antibodies to specific ion channels. The field of autoimmune channelopathies is continuing to expand with identification of new antibody-mediated diseases including those affecting the central nervous system. This review will highlight some of his most seminal findings and those that are following on from his work.

References

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Apr 1, 2003·Annals of Neurology·Paola DaltonAngela Vincent
Feb 26, 2005·Annals of Neurology·Maria Isabel LeiteAngela Vincent
Aug 10, 2005·The Journal of Experimental Medicine·Vanda A LennonShannon R Hinson
Dec 14, 2005·Neurology·K McKnightB Lang
May 5, 2006·Brain : a Journal of Neurology·Maria Elena FarrugiaAngela Vincent
Jul 22, 2006·Journal of Neuroimmunology·Neli BonevaSonia Berrih-Aknin
Jul 28, 2006·Epilepsy Research·H J Marian MajoieAngela Vincent
Oct 4, 2006·Neuron·Angela VincentKleopas A Kleopa
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Jun 3, 2008·Brain : a Journal of Neurology·Maria Isabel LeiteAngela Vincent
Jul 16, 2008·Archives of Neurology·Patrick WatersAngela Vincent

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Citations

Apr 1, 2009·Molecular & Cellular Proteomics : MCP·Edward LittletonAngela Vincent
Oct 1, 2013·Multiple Sclerosis and Related Disorders·Mary Sedarous, Dale J Lange
Dec 24, 2016·The Neurologist·Bernadette Kalman
Jul 21, 2017·Frontiers in Immunology·Shenghua ZongPilar Martinez-Martinez
Mar 11, 2010·Current Opinion in Neurology

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