Autoimmune encephalitis: the first observational study from Iran.

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Masoud EtemadifarMehri Salari


Even within the most populous countries in the Middle East, such as Iran, autoimmune encephalitis cases have been rarely reported. We aimed to describe the demographic, clinical, and paraclinical characteristics of Iranian patients with autoimmune encephalitis positive for anti-neuronal autoantibodies. This cross-sectional study included all patients diagnosed with autoimmune encephalitis and referred to our hospital, in Isfahan, Iran, from March 2016 to May 2020. Patients' demographic, clinical, laboratory, radiological, and electroencephalographic features were obtained from their medical records. We identified a total of 39 (21 females, 53.8%) patients with autoimmune encephalitis (mean age = 34.9 ± 12.8 years). The most commonly detected antibody was anti-NMDAR (n = 26, 66.7%), followed by anti-GABABR (n = 8, 20.5%), anti-Zic4 (n = 4, 10.3%), and anti-GAD65 (n = 1, 2.6%) antibodies, in descending order of frequency. Two anti-NMDAR-positive patients had a history of systemic lupus erythematosus (SLE), and four had a prior history of herpes simplex encephalitis. Clinical presentations in patients positive for anti-Zic4 antibodies included cognitive decline (n = 4, 100%), seizures (n = 3, 75%), parkinsonism (n = 1, 25%), and s...Continue Reading


Jun 23, 2004·Molecular and Cellular Neurosciences·Jun Aruga
Jul 20, 2004·Journal of Neurology, Neurosurgery, and Psychiatry·F GrausR Voltz
Aug 9, 2013·Neurology·Oliver J JefferyAndrew McKeon
May 24, 2014·Annals of Neurology·Liane DahmHannelore Ehrenreich
Jun 17, 2015·Seizure : the Journal of the British Epilepsy Association·Rui WangDong Zhou
Feb 26, 2016·Lancet Neurology·Francesc GrausJosep Dalmau
Apr 1, 2016·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Maude-Marie Gagnon, Martin Savard
Sep 4, 2016·Neurology·Agnes van SonderenMaarten J Titulaer
Nov 8, 2016·Journal of Clinical Neurology·Ying Ying WuJie Wen Zhang
Dec 28, 2016·Annals of Neurology·Tae-Joon KimKon Chu
Dec 28, 2016·Annals of Neurology·Agnes van SonderenMaarten J Titulaer
Apr 19, 2017·Nature Reviews. Neurology·Agnes van SonderenMaarten J Titulaer
May 21, 2017·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Yan ZhangYing Ying Su
May 26, 2017·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·M CelicaninL H Pinborg
Jan 3, 2018·Annals of Neurology·Divyanshu DubeyEoin P Flanagan
Apr 2, 2018·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Stephen BacchiDavid Menon
Nov 22, 2018·Journal of Neurology·Aurélien MaureilleJérôme Honnorat
Jul 28, 2019·Parkinsonism & Related Disorders·Ali Reza TavasoliMohammad Rohani
Aug 2, 2019·International Journal of Preventive Medicine·Atousa HakamifardSeyed Sohrab Hashemi Fesharaki
Aug 5, 2019·Journal of the Neurological Sciences·Rima El-AbassiJohn D England
Feb 23, 2020·Journal of Neuroimmunology·Francisco BernardoMariana Santos
Aug 13, 2020·Brain and Behavior·Prinska GhimireRajeev Ojha
Nov 12, 2020·Archives of Women's Mental Health·Shujiang ZhangZuoxiao Li

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anti-N-Methyl-D-Aspartate Receptor Encephalitis

Anti-N-Methyl-D-Aspartate (NMDA) receptor encephalitis is a form of of brain inflammation due to antibodies against NMDA receptors. Discover the latest research on anti-NMDA receptor encephalitis here.

Related Papers

Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i
Georgiana CraciunPetronela Nechita
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
E E VaseninaD I Levikov
© 2021 Meta ULC. All rights reserved