Autoimmune pancytopenia as an early complication of liver transplantation: report of one case

Leukemia & Lymphoma
Charikleia KelaïdiDidier Bouscary

Abstract

We describe here an immune pancytopenia occurring soon after liver transplantation. Viral causes and allo- and/or auto-antibodies transferred with the graft have been excluded. The condition was concomitant with symptoms compatible with clinical onset of acute graft-versus-host disease. Both pancytopenia and clinical symptoms resolved rapidly under prednisone and intravenous immunoglobulins. We believe that the immune pancytopenia was due to the passive transfer of donor's lymphocytes within the graft and their persistence in peripheral blood in the recipient.

References

Sep 20, 1990·The New England Journal of Medicine·P J FriendJ G McFarland
Mar 17, 1988·The New England Journal of Medicine·J F BurdickB A Perler
Nov 1, 1984·The New England Journal of Medicine·G RamseyG D Lindsay
Oct 1, 1993·Transplantation·H J SchlittR Pichlmayr
Nov 24, 1999·The New England Journal of Medicine·K A WestJ G Kelton

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Citations

Apr 26, 2021·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Melca Maria Oliveira BarrosJose Orlando Bordin

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