Autoimmune progesterone dermatitis

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology
Barbara CocurocciaGiampiero Girolomoni

Abstract

Autoimmune progesterone dermatitis (APD) is a rare disorder characterized by recurrent polymorphous skin manifestations, which appear or are exacerbated during the luteal phase of the menstrual cycle. The hallmarks for diagnosis include premenstrual flare, its prevention with the inhibition of ovulation, and positive skin reaction to intradermal injection of progesterone. The mainstay of treatment is to inhibit the secretion of endogenous progesterone by suppressing ovulation. Bilateral oophorectomy may be necessary in patients with severe and refractory symptoms. We report herein the case of a 38-year-old woman who developed recurrent and cyclic vesiculobullous eruptions clinically suggestive of erythema multiforme or autoimmune bullous diseases. The skin manifestations turned out to be APD. The patient was treated with tamoxifen 20 mg daily with complete symptom remission after 4 months.

References

Sep 1, 1987·The Journal of Allergy and Clinical Immunology·J E Slater, M Kaliner
Jul 1, 1989·The British Journal of Dermatology·C J StephensJ D Wilkinson
Nov 8, 1984·The New England Journal of Medicine·W J MeggsM Kaliner
Feb 1, 1995·Journal of the American Academy of Dermatology·A J HerzbergV A Cirillo-Hyland
Jan 1, 1994·The British Journal of Dermatology·K C Yee, W J Cunliffe
Nov 14, 1997·International Journal of Dermatology·E ShaharS Pollack
Jun 10, 1998·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·B K MoghadamB F Barker
Oct 10, 1998·The British Journal of Dermatology·J M RódenasJ Tercedor
Nov 15, 2000·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·C VasconcelosJ Mesquita-Guimarães
May 31, 2003·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Joy L Snyder, Guha Krishnaswamy
Jul 2, 2003·Journal of the American Academy of Dermatology·Diya F Mutasim, Jennifer L Baumbach
Oct 5, 1964·JAMA : the Journal of the American Medical Association·W B SHELLEYS S SPOONT

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Citations

Mar 17, 2010·Journal of the American Academy of Dermatology·Anna PeroniGiampiero Girolomoni
Nov 12, 2015·Autoimmunity Reviews·Tegan Nguyen, A Razzaque Ahmed
Apr 2, 2008·International Journal of Dermatology·Hobart W Walling, Richard K Scupham
Sep 21, 2010·Journal of Cutaneous Pathology·Teresa J NasabzadehSuraj Venna
May 14, 2011·Clinical and Experimental Dermatology·L M Toms-WhittleD A Buckley
May 27, 2010·Clinical and Experimental Dermatology·S MedeirosJ Cardoso
Oct 22, 2016·Journal of Cutaneous Pathology·Travis JamesAnn LaFond
Jul 23, 2011·Dermatology : International Journal for Clinical and Investigative Dermatology·F PoffetL Borradori
Jan 20, 2018·Current Allergy and Asthma Reports·Rung-Chi LiJonathan A Bernstein
Dec 23, 2008·Obstetrical & Gynecological Survey·Miranda A FarageAllan B MacLean
Nov 12, 2009·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Eliana M MinicucciDaniel Araki Ribeiro
Jan 30, 2020·Current Allergy and Asthma Reports·Jonathan A Bernstein
Oct 12, 2020·The Journal of Allergy and Clinical Immunology. in Practice·Ana Dioun BroylesMariana Castells
Apr 26, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Jonathan A BernsteinMaria Staevska

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