Autoimmune pulmonary alveolar proteinosis mimicking Mycoplasma pneumonia in an adolescent

Respiratory Medicine Case Reports
Shaiva Ginoya MekaBassel A Salman

Abstract

Pulmonary alveolar proteinosis (PAP) is a rare disease of abnormal surfactant production and accumulation. It is typically divided into three main categories: autoimmune, secondary and genetic. The genetic type is more common in children and adolescents, while the autoimmune type is most commonly seen in adults. Here we present an unusual case of autoimmune PAP presenting in an adolescent by mimicking findings of Mycoplasma pneumonia. Although both PAP and Mycoplasma pneumonia may reveal the same findings of the "crazy paving pattern" on computed tomography imaging, it is imperative to distinguish the two as treatment options are dissimilar.

References

Dec 26, 2003·The New England Journal of Medicine·Bruce C TrapnellKoh Nakata
Jun 3, 2011·European Respiratory Review : an Official Journal of the European Respiratory Society·R BorieB Crestani
Aug 16, 2016·Clinics in Chest Medicine·Takuji Suzuki, Bruce C Trapnell
Feb 6, 2018·The Lancet. Respiratory Medicine·Anupam KumarDaniel A Culver

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Citations

Jul 10, 2021·Journal of Medical Case Reports·Abdalla Mohmed AlasiriRabab Nasir Badri

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Methods Mentioned

BETA
bronchoalveolar lavage
biopsy
lavage
enzyme-linked immunosorbent assay

Related Concepts

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Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

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