Autoimmunity in 2014

Clinical Reviews in Allergy & Immunology
Carlo Selmi

Abstract

Our PubMed search for peer-reviewed articles published in the 2014 solar year retrieved a significantly higher number of hits compared to 2013 with a net 28 % increase. Importantly, full articles related to autoimmunity constitute approximately 5 % of immunology articles. We confirm that our understanding of autoimmunity is becoming a translational paradigm with pathogenetic elements rapidly followed by new treatment options. Furthermore, numerous clinical and pathogenetic elements and features are shared among autoimmune diseases, and this is well illustrated in the recent literature. More specifically, the past year witnessed critical revisions of our understanding and management of antiphospholipid syndrome with new exciting data on the pathogenicity of the serum anti-beta2 glycoprotein autoantibody, a better understanding of the current and new treatments for rheumatoid arthritis, and new position papers on important clinical questions such as vaccinations in patients with autoimmune disease, comorbidities, or new classification criteria. Furthermore, data confirming the important connections between innate immunity and autoimmunity via toll-like receptors or the critical role of T regulatory cells in tolerance breakdown an...Continue Reading

References

Jan 25, 2013·Clinical Reviews in Allergy & Immunology·Cecilia Beatrice ChighizolaPier Luigi Meroni
Apr 3, 2013·Clinical Reviews in Allergy & Immunology·Joana Caetano-LopesJoão E Fonseca
Jun 19, 2013·Autoimmunity Reviews·Alessandra GeremiaAntonio Di Sabatino
Jun 19, 2013·Autoimmunity Reviews·Giovanni MonteleoneFrancesco Pallone
Jun 19, 2013·Autoimmunity Reviews·Fabiola AtzeniPiercarlo Sarzi-Puttini
Jun 20, 2013·Autoimmunity Reviews·Andrea CassinottiSandro Ardizzone
Jun 25, 2013·Autoimmunity Reviews·Shomron Ben-HorinYehuda Chowers
Jul 19, 2013·Clinical Reviews in Allergy & Immunology·Vivian Hernandez-Trujillo
Jul 24, 2013·Clinical Reviews in Allergy & Immunology·Mark Ballow
Sep 5, 2013·Autoimmunity Reviews·Henrique Luiz StaubMoisés Evandro Bauer
Sep 17, 2013·Autoimmunity Reviews·Evripidis KaltsonoudisAlexandros A Drosos
Sep 21, 2013·Autoimmunity Reviews·Sara De CarolisMaria Pia De Carolis
Sep 21, 2013·Autoimmunity Reviews·Donato RiganteSusanna Esposito
Sep 21, 2013·Autoimmunity Reviews·Laurent ArnaudZahir Amoura
Sep 24, 2013·Autoimmunity Reviews·Maurizio Cutolo
Oct 15, 2013·Autoimmunity·Tinhinane FaliYves Renaudineau
Oct 17, 2013·Autoimmunity·Zachary Oaks, Andras Perl
Oct 17, 2013·Autoimmunity·Aijing Liu, Antonio La Cava
Oct 23, 2013·Autoimmunity Reviews·Horacio BermanUNKNOWN Catastrophic Registry Project Group (European Forum on Antiphospholipid Antibodies)
Nov 6, 2013·Autoimmunity Reviews·Guillermo Ruiz-IrastorzaMunther Khamashta
Nov 6, 2013·Autoimmunity Reviews·Junfeng ZhengXinhua Yu
Nov 6, 2013·Autoimmunity Reviews·Alessandro AntonelliPoupak Fallahi
Nov 13, 2013·Autoimmunity·Inez RogatskyAlessandra B Pernis
Nov 16, 2013·Autoimmunity·Johanna T Gustafsson, Elisabet Svenungsson
Dec 20, 2013·Clinical Reviews in Allergy & Immunology·Yu LiuQianjin Lu
Dec 24, 2013·Journal of Autoimmunity·Nili AvidanAriel Miller
Dec 24, 2013·Clinical Reviews in Allergy & Immunology·Yoshimasa SaitoJeffrey M Friedman
Jan 7, 2014·Journal of Autoimmunity·Sinisa SavicMichael F McDermott
Jan 7, 2014·Journal of Autoimmunity·Sonia Berrih-Aknin, Rozen Le Panse
Jan 15, 2014·Journal of Autoimmunity·Raphaèle SerorClaudio Vitali
Jan 15, 2014·Autoimmunity Reviews·Xuyan Yang, Song Guo Zheng
Jan 15, 2014·Autoimmunity Reviews·Carlo Selmi, M Eric Gershwin
Jan 15, 2014·Autoimmunity Reviews·R CerveraI Boucot

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Citations

Jul 17, 2016·Clinical Reviews in Allergy & Immunology·Carlo Selmi
May 31, 2017·Clinical Reviews in Allergy & Immunology·Carlo Selmi

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Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

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