Autologous bone graft: when shall we add growth factors?

The Orthopedic Clinics of North America
Peter V Giannoudis, Haralampos T Dinopoulos

Abstract

Although the unquestionable value of autologous bone grafting and the analogous value of the reaming by-products in nonunion treatment have been mentioned extensively in the literature, there is ongoing vivid discussion for the treatment of those case scenarios where the fracture nonunion is complicated by other local environment adverse circumstances. The graft expansion with growth factors as the bone morphogenetic proteins (BMPs) offers the possibility to reduce the number of operative procedures, complications, length of hospital stay, and time to union. In this article, we consider the potential clinical scenarios for graft expansion with BMPs.

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Citations

Oct 2, 2013·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Karim M Fawzy El-SayedSebastian Paris
Apr 15, 2011·Injury·Aaron NauthEmil H Schemitsch
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Nov 21, 2015·BMC Musculoskeletal Disorders·Lars HelbigGerhard Schmidmaier
Jan 6, 2012·The Journal of Bone and Joint Surgery. British Volume·D Herscovici, J M Scaduto
Jun 7, 2019·The Journal of Bone and Joint Surgery. American Volume·Alain MasqueletPeter V Giannoudis
Feb 6, 2013·Orthopedics·Johannes StruewerThomas Manfred Frangen
Oct 5, 2011·Injury·Nikolaos K KanakarisPeter V Giannoudis

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