Autologous chondrocyte implantation: current surgery and rehabilitation

Medicine and Science in Sports and Exercise
Cheryl L Riegger-KrughDavid A Wegzyn

Abstract

Autologous chondrocyte implantation (ACI) is a treatment option for full-thickness chondral, or osteochondral injuries that are painful, debilitating, and progressive. Goals of surgery and rehabilitation include replacement of damaged cartilage with hyaline or hyaline-like structure, maintained durability to withstand knee intraarticular forces over time with a productive level of function, and restoration of the normal surface congruity of the joint. Intermediate and long-term results are promising in terms of clinical improvement and durability using ACI. This article outlines the surgical technique, the histological and biomechanical principles on which the surgery and rehabilitation process are based, and a recommended rehabilitation protocol.

References

Oct 6, 1994·The New England Journal of Medicine·M BrittbergL Peterson
Feb 1, 1996·The Journal of Orthopaedic and Sports Physical Therapy·C Riegger-Krugh, J J Keysor
Jun 3, 1998·Current Opinion in Rheumatology·M V Hurley
Oct 24, 1998·The Journal of Orthopaedic and Sports Physical Therapy·N P CohenV C Mow
Oct 24, 1998·The Journal of Orthopaedic and Sports Physical Therapy·J J Irrgang, D Pezzullo
Nov 11, 1998·The Journal of Orthopaedic and Sports Physical Therapy·R P Grelsamer, J R Klein
Feb 5, 2000·Clinical Biomechanics·G McGintyD Pezzullo
Dec 26, 2001·Clinical Journal of Sport Medicine : Official Journal of the Canadian Academy of Sport Medicine·L J MicheliD Zurakowski
Jan 19, 2002·The American Journal of Sports Medicine·Lars PetersonAnders Lindahl
May 2, 2003·The Journal of Bone and Joint Surgery. American Volume·Lars PetersonAnders Lindahl
Mar 1, 1959·Physical Therapy Reviews : PTR·M WILLIAMS, L STUTZMAN
Dec 13, 2003·The Journal of Orthopaedic and Sports Physical Therapy·Christopher M Powers
Mar 5, 2004·The Journal of Bone and Joint Surgery. American Volume·Gunnar KnutsenOddmund Johansen
Jan 8, 2005·Clinics in Sports Medicine·Paul K Ritchie, Eric C McCarty
Jul 5, 2005·Clinical Orthopaedics and Related Research·Jon E BrowneChristoph Erggelet
Jan 27, 2006·The American Journal of Sports Medicine·Karen HamblyStefan Marlovits
Aug 11, 2006·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Kevin B ShelburneMarcus G Pandy
Oct 27, 2006·The Journal of Orthopaedic and Sports Physical Therapy·Paul B LewisBrian J Cole
Oct 27, 2006·The Journal of Orthopaedic and Sports Physical Therapy·Scott D GilloglyMichael M Reinold
Oct 27, 2006·The Journal of Orthopaedic and Sports Physical Therapy·Hubert T KimMarc R Safran
Oct 27, 2006·The Journal of Orthopaedic and Sports Physical Therapy·Michael M ReinoldE Lyle Cain
Nov 23, 2006·The Journal of Bone and Joint Surgery. American Volume·Deryk G Jones, Lars Peterson
Dec 13, 2006·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Ian HendersonPatrick Lavigne

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Citations

Nov 2, 2013·The Journal of Orthopaedic and Sports Physical Therapy·Peter K EdwardsJay R Ebert
Dec 25, 2012·Archives of Orthopaedic and Trauma Surgery·Stephan VogtHermann O Mayr
Apr 5, 2014·Clinics in Sports Medicine·Mark V PaternoLaura C Schmitt
Sep 25, 2012·Cell Biochemistry and Function·Luisa GenneroRocco De Siena
Apr 27, 2013·The American Journal of Sports Medicine·Jay R EbertTimothy R Ackland
May 24, 2011·The American Journal of Sports Medicine·Anja HirschmüllerPhilipp Niemeyer
Sep 17, 2010·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Haris S VasiliadisLars Peterson
Jan 19, 2021·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Jay R EbertGregory C Janes

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