Autologous fat grafting efficacy in treating PostMastectomy pain syndrome: A prospective multicenter trial of two Senonetwork Italia breast centers.

The Breast Journal
Andrea LisaMarco Klinger

Abstract

Postmastectomy pain syndrome (PMPS) represents a common complication following breast surgery defined as a chronic neuropathic pain located in the front of the chest, in the axilla and in the upper arm that for more than 3 months after surgery. Several medications prove to be ineffective while autologous fat grafting revealed to be an innovative solution in the treatment of neuropathic pain syndromes based on retrospective studies. For this reason, we performed a prospective multicenter trial to reduce the memory bias and further increase the evidence of the results. From February 2018 to March 2019, 37 female patients aged between 18 and 80 years, underwent mastectomy or quadrantectomy with pathologic scarring and chronic persistent neuropathic pain, compatible with PMPS, are been included in the study and treated with autologous fat grafting. During the enrollment phase, patients were asked to estimate pain using the Visual Analogue Scale (VAS) and POSAS questionnaire in order to evaluate scar outcomes. The VAS scale, starting from 6.9 (1.3), decreased in the first month by 3.10 (1.59), continuing to fall by 0.83 (1.60) to 3 months and by 0.39 (2.09) at 6 months. Statistical analysis showed a significant reduction after 1 mon...Continue Reading

References

Dec 1, 1992·Pain·Peter N C Watson, Ramon J Evans
Mar 13, 2002·European Journal of Pain : EJP·Tiina TasmuthEija Kalso
Aug 22, 2007·Cell Transplantation·Kirsten A KeyserHans-Peter Kiem
Jun 21, 2008·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·O J VilholmS H Sindrup
Jul 1, 2008·The Journal of Pain : Official Journal of the American Pain Society·Monique A SteegersOliver H Wilder-Smith
Oct 22, 2009·Anesthesia and Analgesia·Israel Z YardeniHanna Bessler
Dec 3, 2010·Plastic and Reconstructive Surgery·Hirotaka SugaKotaro Yoshimura
Jul 27, 2011·Plastic and Reconstructive Surgery·Fabio CaviggioliMarco Klinger
Jun 6, 2015·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Steven PikeYuan Liu
Feb 10, 2016·Stem Cells International·Fabio CaviggioliMarco Klinger
Dec 20, 2017·Plastic and Reconstructive Surgery·Junrong CaiFeng Lu
Jan 6, 2018·Orbit·Francesco KlingerAlessandra Di Maria
Jul 4, 2018·The Journal of Pain : Official Journal of the American Pain Society·Raymond C TaitChristopher Herndon
Mar 2, 2019·Aesthetic Plastic Surgery·Alp ErcanOguz Cetinkale
Nov 20, 2019·Clinics in Plastic Surgery·Marco KlingerValeriano Vinci

❮ Previous
Next ❯

Citations

Sep 11, 2020·The Breast Journal·Domenico CostanzoValeriano Vinci
Apr 15, 2021·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Andrea RimondoFrancesco Klinger
Apr 23, 2021·Aesthetic Plastic Surgery·Rong HuangZhiguo Su
Apr 24, 2021·Aesthetic Plastic Surgery·Andrea BattistiniFrancesco Klinger
May 29, 2021·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Andrea BattistiniFrancesco Klinger
May 31, 2021·Clinical Breast Cancer·Andrea LisaMarco Klinger
Jul 30, 2021·Aesthetic Surgery Journal·Fabio CaviggioliValeriano Vinci
Oct 5, 2021·Plastic and Reconstructive Surgery·Andrea BattistiniFrancesco Klinger
Oct 5, 2021·Aesthetic Surgery Journal·Summer E Hanson
Jan 26, 2022·Plastic and Reconstructive Surgery·Martin SollieJens Ahm Sørensen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.