Automated beam placement for breast radiotherapy using a support vector machine based algorithm

Medical Physics
Xuan ZhaoYao Wang

Abstract

To develop an automated beam placement technique for whole breast radiotherapy using tangential beams. We seek to find optimal parameters for tangential beams to cover the whole ipsilateral breast (WB) and minimize the dose to the organs at risk (OARs). A support vector machine (SVM) based method is proposed to determine the optimal posterior plane of the tangential beams. Relative significances of including/avoiding the volumes of interests are incorporated into the cost function of the SVM. After finding the optimal 3-D plane that separates the whole breast (WB) and the included clinical target volumes (CTVs) from the OARs, the gantry angle, collimator angle, and posterior jaw size of the tangential beams are derived from the separating plane equation. Dosimetric measures of the treatment plans determined by the automated method are compared with those obtained by applying manual beam placement by the physicians. The method can be further extended to use multileaf collimator (MLC) blocking by optimizing posterior MLC positions. The plans for 36 patients (23 prone- and 13 supine-treated) with left breast cancer were analyzed. Our algorithm reduced the volume of the heart that receives >500 cGy dose (V5) from 2.7 to 1.7 cm(3) (...Continue Reading

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Citations

Jan 16, 2014·Journal of Applied Clinical Medical Physics·Christopher Boylan, Carl Rowbottom
Nov 20, 2019·Journal of Applied Clinical Medical Physics·Bingqi GuoPing Xia
May 23, 2019·Radiological Physics and Technology·Norifumi MizunoTakeo Takahashi
May 12, 2019·Medical Physics·Kelly KislingLaurence Court
Jun 17, 2018·Practical Radiation Oncology·Mariët J van Duren-KoopmanWilko F Verbakel
Nov 13, 2021·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Savino CillaAlessio G Morganti

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