Automated, computer-guided PASI measurements by digital image analysis versus conventional physicians' PASI calculations: study protocol for a comparative, single-centre, observational study

BMJ Open
Christine FinkHolger A Haenssle

Abstract

Reliable and accurate assessment of severity in psoriasis is very important in order to meet indication criteria for initiation of systemic treatment or to evaluate treatment efficacy. The most acknowledged tool for measuring the extent of psoriatic skin changes is the Psoriasis Area and Severity Index (PASI). However, the calculation of PASI can be tedious and subjective and high intraobserver and interobserver variability is an important concern. Therefore, there is a great need for a standardised and objective method that guarantees a reproducible PASI calculation. Within this study we will investigate the precision and reproducibility of automated, computer-guided PASI measurements in comparison to trained physicians to address these limitations. Non-interventional analyses of PASI calculations by either physicians in a prospective versus retrospective setting or an automated computer-guided algorithm in 120 patients with plaque psoriasis. All retrospective PASI calculations by physicians or by the computer algorithm are based on total body digital images. The primary objective of this study is comparison of automated computer-guided PASI measurements by means of digital image analysis versus conventional, prospective or re...Continue Reading

Citations

Feb 5, 2019·The British Journal of Dermatology·I Garcia-Doval, J Albrecht
Apr 12, 2021·The Journal of Allergy and Clinical Immunology. in Practice·Laura MaintzCarolyn Jack
Sep 2, 2019·Actas dermo-sifiliográficas·A ReolidUNKNOWN Grupo de Trabajo de evaluación del Body Surface Area (BSA)

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Software Mentioned

MASS
FotoFinder
FotoFinder PASI Software for Psoriasis Quantification ( PASIvi...
xtable
FotoFinder ATBM
FotoFinder PASI Software for Psoriasis Quantification (
REDCap
car
nlme
psychometric

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