PMID: 8444365Feb 1, 1993Paper

Automated detection and quantification of retinal exudates

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
R PhillipsP Sharp

Abstract

Retinal exudates are a common manifestation of vascular damage in a variety of retinal diseases. We have used computerized image analysis to detect and measure the area of exudates from digitized colour fundus slides of patients with diabetic retinopathy and have assessed the repeatability, reproducibility, and accuracy of the technique. The analysis was entirely independent of the operator apart from choice of the region to be analysed. The coefficient of variation for repeatability was between 3% for large areas of exudate and 17% for small areas of exudate. The reproducibility was also within this range. Sensitivity was between 61 and 100% (mean 87%). False-positives were observed in 5 of 30 regions analysed, and these could have been eliminated by using more stringent criteria for selection of images for analysis. Time taken for the analysis was approximately 3 min.

References

Jan 1, 1992·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·T SpencerJ V Forrester
Jan 1, 1991·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·R P PhillipsJ V Forrester
Apr 15, 1987·Applied Optics·R H WebbF C Delori

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Citations

May 12, 2009·Annals of Biomedical Engineering·María GarcíaRoberto Hornero
May 9, 2008·Journal of Medical Systems·Jagadish NayakManjunath Kagathi
Jul 31, 2013·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·Sharib AliFabrice Mériaudeau
Oct 1, 1995·The British Journal of Ophthalmology·J N KirkpatrickP F Sharp
Jun 25, 2014·Medical & Biological Engineering & Computing·Karthikeyan GanesanAugustinus Laude
Feb 12, 2009·Journal of Medical Engineering & Technology·J NayakU R Acharya
Sep 10, 2008·Computer Methods and Programs in Biomedicine·María GarcíaRoberto Hornero
Jun 9, 2007·Medical Engineering & Physics·Clara I SánchezDaniel Abásolo
Jun 26, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·J A OlsonP F Sharp
Jul 12, 2014·IEEE Journal of Biomedical and Health Informatics·Carla AgurtoPeter Soliz
Jun 10, 2006·IEEE Transactions on Bio-medical Engineering·Harihar Narasimha-IyerHanumant Singh
Jul 10, 2009·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Alireza OsarehRichard Markham
Feb 10, 2004·IEEE Transactions on Bio-medical Engineering·Huiqi Li, Opas Chutatape
Aug 6, 2019·Medical Physics·Qifeng YanJiang Liu
May 1, 1997·Physics in Medicine and Biology·P F Sharp, A Manivannan
Mar 11, 1999·Physics in Medicine and Biology·M J CreeJ V Forrester
Feb 15, 2011·Journal of Medical Systems·Haniza YazidHazlita Mohd Isa

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