Automated Diabetic Retinopathy Screening and Monitoring Using Retinal Fundus Image Analysis

Journal of Diabetes Science and Technology
Malavika BhaskaranandKaushal Solanki

Abstract

Diabetic retinopathy (DR)-a common complication of diabetes-is the leading cause of vision loss among the working-age population in the western world. DR is largely asymptomatic, but if detected at early stages the progression to vision loss can be significantly slowed. With the increasing diabetic population there is an urgent need for automated DR screening and monitoring. To address this growing need, in this article we discuss an automated DR screening tool and extend it for automated estimation of microaneurysm (MA) turnover, a potential biomarker for DR risk. The DR screening tool automatically analyzes color retinal fundus images from a patient encounter for the various DR pathologies and collates the information from all the images belonging to a patient encounter to generate a patient-level screening recommendation. The MA turnover estimation tool aligns retinal images from multiple encounters of a patient, localizes MAs, and performs MA dynamics analysis to evaluate new, persistent, and disappeared lesion maps and estimate MA turnover rates. The DR screening tool achieves 90% sensitivity at 63.2% specificity on a data set of 40 542 images from 5084 patient encounters obtained from the EyePACS telescreening system. On ...Continue Reading

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Citations

Apr 15, 2017·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association
Sep 25, 2017·Current Diabetes Reports·Lucy I MudieChristopher J Brady
Jan 18, 2018·Ophthalmic Research·Mads Fonager Nørgaard, Jakob Grauslund
Sep 17, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Valentina SaraoPaolo Lanzetta
Nov 19, 2019·Translational Vision Science & Technology·Feng LiZhizheng Wu
May 16, 2019·Acta Diabetologica·Matias IglickiUNKNOWN International Retina Group (IRG)
Mar 31, 2020·Acta Diabetologica·Paolo LanzettaUNKNOWN Vision Academy
Mar 30, 2017·Medical & Biological Engineering & Computing·Qaisar AbbasPedro Alemany
Sep 20, 2017·Acta Ophthalmologica·Kang WangSriniVas R Sadda
Dec 27, 2018·International Ophthalmology Clinics·Rishabh C DateChristina Y Weng
Jun 27, 2020·Indian Journal of Ophthalmology·Sreetama DuttRamachandran Rajalakshmi
Sep 11, 2020·Translational Vision Science & Technology·Ryan Y YehJonathan Cagan
Nov 16, 2020·Journal of Diabetes Investigation·Nicola QuinnLaima Brazionis
Feb 5, 2021·Seminars in Ophthalmology·Michael J Gilbert, Jennifer K Sun
Mar 14, 2021·Diabetes/metabolism Research and Reviews·Yuelin WangYouxin Chen
Jun 25, 2021·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Luis Filipe NakayamaCaio Vinicius Saito Regatieri
Aug 13, 2021·Asia-Pacific Journal of Ophthalmology·Rachel Marjorie Wei Wen TsengYih-Chung Tham
Sep 23, 2021·Journal of Diabetes Science and Technology·Or KatzDavid R Owens
Jan 8, 2022·Chinese Medical Journal·Sicong LiHaidong Zou

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Software Mentioned

EyeMark
EyeArt
EyePACS

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