Automated mandatory bolus versus basal infusion for maintenance of epidural analgesia in labour

The Cochrane Database of Systematic Reviews
Ban Leong SngA T H Sia

Abstract

Childbirth may cause the most severe pain some women experience in their lifetime. Epidural analgesia is an effective form of pain relief during labour and is considered to be the reference standard. Traditionally epidural analgesia has been delivered as a continuous infusion via a catheter in the epidural space, with or without the ability for the patient to supplement the analgesia received by activating a programmable pump to deliver additional top-up doses, known as patient-controlled epidural analgesia (PCEA). There has been interest in delivering maintenance analgesic medication via bolus dosing (automated mandatory bolus - AMB) instead of the traditional continuous basal infusion (BI); recent randomized controlled trials (RCTs) have shown that the AMB technique leads to improved analgesia and maternal satisfaction. To assess the effects of automated mandatory bolus versus basal infusion for maintaining epidural analgesia in labour. We searched CENTRAL, MEDLINE, Embase, the World Health Organization International Clinial Trials Registry Platform (WHO-ICTRP) and ClinicalTrials.gov on 16 January 2018. We screened the reference lists of all eligible trials and reviews. We also contacted authors of included studies in this fi...Continue Reading

References

May 1, 1988·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D R GamblingL Palmer
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Jun 16, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Sebastian M H Chua, Alex T H Sia
Sep 13, 2005·International Journal of Obstetric Anesthesia·Y LimC Ocampo
Jul 20, 2006·British Journal of Anaesthesia·P D W FettesJ A W Wildsmith
May 6, 2008·BMJ : British Medical Journal·Gordon H GuyattUNKNOWN GRADE Working Group
May 8, 2015·Journal of Anaesthesiology, Clinical Pharmacology·Chinmayi Surendra PatkarGeeta Parikh
Jul 30, 2016·Therapeutics and Clinical Risk Management·Yunan LinJingchen Liu

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