PMID: 6397087Dec 1, 1984Paper

Automated measurement of acid phosphatase reaction product in human kidneys treated with aminoglycoside antibiotics

Analytical and Quantitative Cytology
A CornelisF Roels

Abstract

The acid phosphatase reaction product was measured by automated image analysis densitometry in histologic sections from 23 human kidney biopsies. Optical density was proportional to incubation time, section thickness and enzyme activity. After a four days' treatment with aminoglycoside antibiotics, optical density was increased and paralleled the lysosomal changes previously observed by electron microscopy.

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Aminoglycosides (ASM)

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

Aminoglycosides

Aminoglycoside is a medicinal and bacteriologic category of traditional Gram-negative antibacterial medications that inhibit protein synthesis and contain as a portion of the molecule an amino-modified glycoside. Discover the latest research on aminoglycoside here.

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