Automated multi-parameter high-dose-rate brachytherapy quality assurance via radioluminescence imaging

Physics in Medicine and Biology
Mengyu JiaBenjamin P Fahimian

Abstract

The purpose of this study is to leverage radioluminescence imaging for the development of an automated high-dose-rate (HDR) brachytherapy quality assurance (QA) system that enables simultaneous measurements of dwell position, dwell time, wire velocity, and relative source strength in a single test. The system consists of a radioluminescence phosphor sheet (a mixture of Gd2O2S:Tb and PDMS) positioned atop a HDR needle applicator, a complementary metal-oxide-semiconductor digital camera used to capture the emitted radioluminescence signals from the scintillator sheet, and an in-house graphical user interface for signal processing. The signal processing was used to extract source intensity, location, and elapsed time, yielding the final measurements on dwell position, dwell time, and wire velocity. The source strength relative to the well chamber calibration (in unit of Air-Kerma strength, Sk ) is measured by establishing a calibration curve that correlates Sk with the detector response. Validation experiments are performed using three customized treatment plans. With these plans, the dwell position and dwell time are verified for a range of 110.0 cm-117.5 cm and 2 s-16 s, respectively, and the linear correlation with Sk is demons...Continue Reading

References

Feb 24, 2007·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·M D C EvansE B Podgorsak
May 29, 2009·Medical Physics·Haijun SongFang-Fang Yin
Jul 17, 2010·Medical Physics·Daniel W RickeyJeff Bews
Jun 14, 2017·Physics in Medicine and Biology·Gabriel P FonsecaFrank Verhaegen
Sep 16, 2017·Physics in Medicine and Biology·Gabriel P FonsecaFrank Verhaegen
Mar 21, 2019·Medical Physics·Haydee M Linares RosalesLuc Beaulieu
Jul 23, 2019·Brachytherapy·Murillo BellezzoGabriel P Fonseca

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Citations

Jun 17, 2021·Physics in Medicine and Biology·Jiawei FanYong Yang

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