Automated quantification of stenosis severity on 64-slice CT: a comparison with quantitative coronary angiography

JACC. Cardiovascular Imaging
Mark J BoogersJ J Bax

Abstract

This study sought to demonstrate the feasibility of a dedicated algorithm for automated quantification of stenosis severity on multislice computed tomography in comparison with quantitative coronary angiography (QCA). Limited information is available on quantification of coronary stenosis, and previous attempts using semiautomated approaches have been suboptimal. In patients who had undergone 64-slice computed tomography and invasive coronary angiography, the most severe lesion on QCA was quantified per coronary artery using quantitative coronary computed tomography (QCCTA) software. Additionally, visual grading of stenosis severity using a binary approach (50% stenosis as a cutoff) was performed. Diameter stenosis (percentage) was obtained from detected lumen contours at the minimal lumen area, and corresponding reference diameter values were obtained from an automatic trend analysis of the vessel areas within the artery. One hundred patients (53 men; 59.8 +/- 8.0 years) were evaluated, and 282 (94%) vessels were analyzed. Good correlations for diameter stenosis were observed for vessel-based (n = 282; r = 0.83; p < 0.01) and patient-based (n = 93; r = 0.86; p < 0.01) analyses. Mean differences between QCCTA and QCA were -3.0%...Continue Reading

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Citations

Jun 4, 2011·The International Journal of Cardiovascular Imaging·Guanyu YangJouke Dijkstra
Apr 10, 2012·International Journal of Computer Assisted Radiology and Surgery·Roman GoldenbergNathan Peled
May 30, 2013·European Journal of Nuclear Medicine and Molecular Imaging·Michiel A de GraafArthur J Scholte
Aug 6, 2014·Cardiology Clinics·Swapnesh Parikh, Matthew J Budoff
Feb 7, 2012·Cardiology Clinics·Stephan Achenbach, Takeshi Kondo
Jun 9, 2012·The Mount Sinai Journal of Medicine, New York·Pamela T Johnson, Elliot K Fishman
Feb 1, 2011·Archives of Cardiovascular Diseases·Edouard CheneauDimitri Panagides
Nov 17, 2015·Heart Failure Clinics·Swapnesh Parikh, Matthew J Budoff
Nov 28, 2013·Circulation. Cardiovascular Imaging·Alexia RossiPim J de Feyter
Nov 14, 2017·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Kengo TanabeTakeshi Kimura
Nov 7, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Maoto HabaraTakahiko Suzuki
Sep 20, 2017·Radiology·Christian TescheU Joseph Schoepf
Aug 12, 2020·The International Journal of Cardiovascular Imaging·Parastou EslamiUdo Hoffmann
Dec 9, 2020·Journal of Clinical Medicine·Francesca BaessatoGianluca Pontone
Nov 28, 2017·Translational Research : the Journal of Laboratory and Clinical Medicine·Ahmad F HedayatLilach O Lerman

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