PMID: 6536211Jan 1, 1984Paper

Automated recording of precision profiles for the radioimmunological determination of T4 using a pocket calculator of the HP-41 CV type

Annales d'endocrinologie
M DituH N Wagner

Abstract

Precision profiles as useful tool for assurance of assay quality in 10 independent T4RIAs have been automatically obtained using a small programmable pocket calculator HP-41 CV. For each T4 assay batch, the within-assay coefficient of variation varied from 7 to 11% in the hormone concentration range of 2 to 20 micrograms/dl. The difference in coefficient of variation for all the 10 successive assay batches of T4, never exceeded 1% in the same hormone concentrations regions. All the above findings demonstrate that the precision profile can be used as a powerful tool for assessing the assay quality and consistency of overall random error between successive assay batches.

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