Automated segmentation of subretinal layers for the detection of macular edema

Applied Optics
Taimur HassanShafaat Ahmed Bazaz

Abstract

Macular edema (ME) is considered as one of the major indications of proliferative diabetic retinopathy and it is commonly caused due to diabetes. ME causes retinal swelling due to the accumulation of protein deposits within subretinal layers. Optical coherence tomography (OCT) imaging provides an early detection of ME by showing the cross-sectional view of macular pathology. Many researchers have worked on automated identification of macular edema from fundus images, but this paper proposes a fully automated method for extracting and analyzing subretinal layers from OCT images using coherent tensors. These subretinal layers are then used to predict ME from candidate images using a support vector machine (SVM) classifier. A total of 71 OCT images of 64 patients are collected locally in which 15 persons have ME and 49 persons are healthy. Our proposed system has an overall accuracy of 97.78% in correctly classifying ME patients and healthy persons. We have also tested our proposed implementation on spectral domain OCT (SD-OCT) images of the Duke dataset consisting of 109 images from 10 patients and it correctly classified all healthy and ME images in the dataset.

References

Mar 9, 1995·Current Opinion in Ophthalmology·J S SchumanE A Swanson
Nov 29, 2008·Arquivos brasileiros de oftalmologia·Rosana Zacarias Hannouche, Marcos Pereira Avila
Dec 12, 2005·Optics Express·Delia Cabrera FernándezCarmen A Puliafito
Feb 22, 2012·Nepalese Journal of Ophthalmology : a Biannual Peer-reviewed Academic Journal of the Nepal Ophthalmic Society : NEPJOPH·A ShresthaG Poudyal

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Citations

Dec 12, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Jacqueline ChuaLeopold Schmetterer
Aug 28, 2019·Biomedical Optics Express·Yibiao RongXinjian Chen
May 4, 2016·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Bilal HassanM Usman Akram
Dec 26, 2018·Journal of Ophthalmology·Wei LuYin Shen
Sep 3, 2020·Scientific Reports·Aqsa Ajaz, Dinesh K Kumar
Jun 17, 2021·Translational Vision Science & Technology·Bo ZhengWei-Hua Yang

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