Automated vs. conventional ventilation in the ICU: a randomized controlled crossover trial comparing blood oxygen saturation during daily nursing procedures (I-NURSING).

Critical Care : the Official Journal of the Critical Care Forum
Jonathan ChellyMehran Monchi

Abstract

Hypoxia is common during daily nursing procedures (DNPs) routinely performed on mechanically ventilated patients. The impact of automated ventilation on the incidence and severity of blood oxygen desaturation during DNPs remains unknown. A prospective randomized controlled crossover trial was carried out in a French intensive care unit to compare blood oxygen pulse saturation (SpO2) during DNPs performed on patients mechanically ventilated in automated and conventional ventilation modes (AV and CV, respectively). All patients with FiO2 ≤ 60% and without prone positioning or neuromuscular blocking agents were included. Patients underwent two DNPs on the same day using AV (INTELLiVENT-ASV®) and CV (volume control, biphasic positive airway pressure, or pressure support ventilation) in a randomized order. The primary outcome was the percentage of time spent with SpO2 in the acceptable range of 90-95% during the DNP. Of the 265 included patients, 93% had been admitted for a medical pathology, the majority for acute respiratory failure (52%). There was no difference between the two periods in terms of DNP duration, sedation requirements, or ventilation parameters, but patients had more spontaneous breaths and lower peak airway pressu...Continue Reading

References

May 1, 1984·Critical Care Medicine·D RivaraC Hiriart
May 1, 1997·Acta Anaesthesiologica Scandinavica·P TanskanenT Randell
Nov 21, 2002·Critical Care Medicine·Sreenandh KrishnagopalanLarry J Kaufman
Mar 5, 2003·American Journal of Respiratory and Critical Care Medicine·Salvatore M MaggioreLaurent Brochard
Sep 30, 2004·Heart & Lung : the Journal of Critical Care·Alice Y M Jones, Elizabeth Dean
Dec 31, 2008·Critical Care Medicine·Stephan M JakobJukka Takala
Jan 5, 2011·Critical Care Medicine·Jesse B Hall
Feb 9, 2011·Nursing in Critical Care·Lyvonne N TumePaulo J G Lisboa
Aug 24, 2012·Current Opinion in Critical Care·Linda Denehy, Doug Elliott
Jan 23, 2013·Intensive Care Medicine·François LelloucheMarc Wysocki
Apr 20, 2013·Critical Care : the Official Journal of the Critical Care Forum·Audrey de JongGérald Chanques
Sep 13, 2013·Critical Care : the Official Journal of the Critical Care Forum·Jean-Michel ArnalJacques Durand-Gasselin
Mar 1, 2014·Intensive Care Medicine·Ashley J R BeijersAlexander J G H Bindels
Sep 5, 2014·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Lena NyholmPer Enblad
Jun 18, 2016·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Sara RedaelliNicolò Patroniti
Sep 14, 2016·Intensive Care Medicine·L GattinoniM Quintel
Aug 3, 2017·Journal of Clinical and Diagnostic Research : JCDR·Anupam Kumar SinghSajjan Rajpurohit
Nov 22, 2018·Annals of Translational Medicine·Mehdi Mezidi, Claude Guérin

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Methods Mentioned

BETA
sedation

Clinical Trials Mentioned

NCT03176329

Software Mentioned

Evolucare Intensive
SPSS Statistics
INTELLiVENT

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