Automatic control of airway pressure for treatment of obstructive sleep apnea

IEEE Transactions on Bio-medical Engineering
K BehbehaniJ R Axe

Abstract

Obstructive sleep apnea (OSA) occurs when airflow ceases because of pharyngeal wall collapse in sleep. Repeated apneic events results in the development of a pathological condition called OSA syndrome. We describe the methodology and design of a prosthetic device, named automatic positive airway pressure (APAP), for treatment of this syndrome. APAP applies a stream of air via a nasal mask at an initial pressure selected by the patient. By sensing specific pressure characteristics of air flow immediately preceding pharyngeal wall collapse, the APAP device automatically raises the applied pressure to maintain a patent upper airway and thus prevent apnea. Conversely, when such conditions are absent, pressure is lowered step wise until a preselected minimum pressure is reached. Performance evaluation of the APAP system in five OSA patients and five normal (asymptomatic for sleep apnea) subjects revealed that it effectively treated OSA syndrome. It lowered the apnea-hypopnea index without disturbing sleep and resulted in a lower mean airway pressure compared to the traditional continuous positive airway pressure (CPAP) therapy. The results also show that the pressure needed to prevent OSA varied significantly throughout the night. F...Continue Reading

References

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Citations

May 1, 1997·Medical & Biological Engineering & Computing·K BehbehaniF Kamangar
Mar 20, 2001·American Journal of Respiratory and Critical Care Medicine·W J RanderathK H Rühle
Feb 3, 2012·Biomedical Engineering Online·Zheng-Long ChenHou-De Dai
Jun 13, 2015·Sleep & Breathing = Schlaf & Atmung·Helder Novais BastosJoão Carlos Winck
Oct 3, 2008·BMC Pulmonary Medicine·Marta DrummondJosé A Marques
Apr 29, 1998·Clinics in Chest Medicine·P J StrolloC W Atwood
Jun 13, 2003·Clinics in Chest Medicine·Francoise J Roux, Janet Hilbert
Aug 8, 2019·Sleep & Breathing = Schlaf & Atmung·S D HerkenrathW J Randerath

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