PMID: 2494902Jan 1, 1989Paper

Automatic control of arterial pressure after cardiac surgery. Evaluation of a microcomputer-based control system using glyceryl trinitrate and sodium nitroprusside

Anaesthesia
J R Colvin, G N Kenny

Abstract

Arterial hypertension after cardiac surgery is common and is associated with increased morbidity. Glyceryl trinitrate may be a more suitable agent for control of hypertension than sodium nitroprusside. We have developed a closed-loop system for the Atari 1040ST microcomputer to control arterial pressure by the simultaneous infusion of two vasodilators under computer control. Use of this system with glyceryl trinitrate and sodium nitroprusside in 24 patients who required vasodilators after cardiopulmonary bypass, revealed that hypertension was controlled by glyceryl trinitrate alone in 14 of the patients and 10 required supplementary sodium nitroprusside. The results suggest that glyceryl trinitrate is a suitable agent for control of hypertension after cardiac surgery in the majority of patients. They also show that a sizeable minority required additional sodium nitroprusside, and that an automated 'dual pump' system is a satisfactory method of administering two vasodilators in this way.

References

Jul 1, 1976·British Journal of Anaesthesia·C J VeseyP J Simpson
Mar 1, 1977·Anesthesiology·J D Michenfelder
Oct 1, 1977·Anesthesiology·P S Colley, F W Cheney
Jan 1, 1987·Intensive Care Nursing·C J Murchie
Feb 1, 1987·British Journal of Anaesthesia·J A Reid, G N Kenny
Oct 1, 1984·Annals of Internal Medicine·T L ShookG A Lamas
Oct 1, 1984·Annals of Internal Medicine·J ShoreyJ Loscalzo
Oct 1, 1980·The American Journal of Cardiology·F G Estafanous, R C Tarazi

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Citations

Mar 1, 1990·Journal of Clinical Pharmacology·G Chun, W H Frishman
Aug 1, 1995·Journal of Clinical Pharmacology·W AbdelwahabA Landau
Jan 1, 1989·International Journal of Clinical Monitoring and Computing·J R Colvin, G N Kenny
Jan 1, 1991·International Journal of Clinical Monitoring and Computing·J R ColvinG N Kenny
Apr 20, 2001·Acta Anaesthesiologica Scandinavica·S A HoekselJ J Schreuder
Oct 3, 2006·Current Opinion in Anaesthesiology·S E Milne, G N Kenny
Jan 1, 1995·IEEE Transactions on Bio-medical Engineering·K E KwokB A Finegan
Apr 1, 1993·IEEE Transactions on Bio-medical Engineering·S Isaka, A V Sebald
Dec 3, 1999·European Journal of Anaesthesiology·S AlbrechtJ Schüttler
Feb 1, 1997·International Journal of Clinical Monitoring and Computing·A J Asbury
Nov 21, 2002·Heart Disease·George A Mansoor, William H Frishman
Sep 1, 1996·Journal of Clinical Monitoring·S A HoekselJ J Schreuder
Feb 11, 2000·The Annals of Pharmacotherapy·B L Erstad, J F Barletta

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