Automatic multiscale enhancement and segmentation of pulmonary vessels in CT pulmonary angiography images for CAD applications

Medical Physics
Chuan ZhouElla A Kazerooni

Abstract

The authors are developing a computerized pulmonary vessel segmentation method for a computer-aided pulmonary embolism (PE) detection system on computed tomographic pulmonary angiography (CTPA) images. Because PE only occurs inside pulmonary arteries, an automatic and accurate segmentation of the pulmonary vessels in 3D CTPA images is an essential step for the PE CAD system. To segment the pulmonary vessels within the lung, the lung regions are first extracted using expectation-maximization (EM) analysis and morphological operations. The authors developed a 3D multiscale filtering technique to enhance the pulmonary vascular structures based on the analysis of eigenvalues of the Hessian matrix at multiple scales. A new response function of the filter was designed to enhance all vascular structures including the vessel bifurcations and suppress nonvessel structures such as the lymphoid tissues surrounding the vessels. An EM estimation is then used to segment the vascular structures by extracting the high response voxels at each scale. The vessel tree is finally reconstructed by integrating the segmented vessels at all scales based on a "connected component" analysis. Two CTPA cases containing PEs were used to evaluate the perform...Continue Reading

References

Jan 1, 1975·Progress in Cardiovascular Diseases·J E Dalen, J S Alpert
Mar 12, 1998·Radiology·G D RubinS Napel
Aug 28, 1998·Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society·K KanazawaK Eguchi
Dec 10, 1999·Medical Physics·C H McCollough, F E Zink
Sep 6, 2000·Medical Image Analysis·T McInerney, D Terzopoulos
Aug 29, 2001·Medical Image Analysis·L M LorigoC F Westin
Apr 4, 2002·IEEE Transactions on Medical Imaging·Stephen R Aylward, Elizabeth Bullitt
Jan 15, 2004·IEEE Transactions on Medical Imaging·Onno WinkMax A Viergever
Jan 1, 1996·IEEE Transactions on Medical Imaging·R Kutka, S Stier
Jan 1, 1996·IEEE Transactions on Medical Imaging·W E HigginsE L Ritman

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Citations

Dec 18, 2013·Artificial Intelligence in Medicine·Antonio Oseas de Carvalho FilhoMarcelo Gattass
Jun 4, 2014·Computer Methods and Programs in Biomedicine·Shih-Feng Yang, Ching-Hsue Cheng
Aug 29, 2009·Computer Methods and Programs in Biomedicine·Rahul ShingraniRobert Molthen
Nov 13, 2009·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Panayiotis D KorfiatisLena I Costaridou
Feb 15, 2011·IEEE Transactions on Information Technology in Biomedicine : a Publication of the IEEE Engineering in Medicine and Biology Society·Panayiotis D KorfiatisLena I Costaridou
Dec 19, 2013·Computational and Mathematical Methods in Medicine·Jiaoying JinMingyue Ding
May 18, 2016·Medical Image Analysis·Christian PayerMartin Urschler
Apr 15, 2016·IEEE Transactions on Medical Imaging·Tim JermanZiga Spiclin
Aug 10, 2017·Veterinary Radiology & Ultrasound : the Official Journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·Anna V MüllerFintan J McEvoy
Oct 19, 2012·Journal of Digital Imaging·Shiloah Elizabeth DarmanayagamKannan Arputharaj
Aug 21, 2013·Physics in Medicine and Biology·Eva M van Rikxoort, Bram van Ginneken
Aug 1, 2014·Physics in Medicine and Biology·Lubomir HadjiiskiSmita Patel
Mar 12, 2019·Journal of X-ray Science and Technology·Hui-Hong DuanSheng-Dong Nie

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