Automatic pressure-assisted dual-headspace gas-liquid microextraction. Lab-in-syringe platform for membraneless gas separation of ammonia coupled with fluorimetric sequential injection analysis

Analytica Chimica Acta
Georgia Giakisikli, Aristidis N Anthemidis

Abstract

A novel pressure-assisted dual-headspace lab-in-syringe microextraction technique is presented as an alternative approach for automatic on-line membraneless gas separation of volatile compounds. The developed gas-liquid microextraction procedure is based on the lab-in-syringe (LIS) concept by using two independent micro-syringe pumps which are connected to each other for the application of negative and positive pressure inside the common headspace area of the syringe barrels. The adoption of reduced and increased pressure conditions is facilitated by the programmable LIS strategy resulting in increased extraction rates. The analytical process includes the in-situ ammonia vapor generation in the headspace of the first microsyringe, under reduced pressure environment, and its subsequent transportation into the headspace of the second microsyringe. Then, positive pressure is applied inside the second microsyringe enabling the ammonia vapor dissolution into the extraction solution to produce a fluorescent product (isoindol-1-sulfonat). The reaction is time and temperature affected, thus after an optimized time of delay inside the thermostated syringe barrel at 60 °C, it is delivered into the flow-cell of the miniSIA system where it...Continue Reading

Citations

Apr 3, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Athina Dimitriadou, Aristidis Anthemidis
Apr 5, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Burkhard Horstkotte, Petr Solich
May 18, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Thitirat MantimDuangjai Nacapricha

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