Automatic quantification of myocardium and pericardial fat from coronary computed tomography angiography: a multicenter study.

European Radiology
Xiuxiu HeXiaofeng Yang

Abstract

To develop a deep learning-based method for simultaneous myocardium and pericardial fat quantification from coronary computed tomography angiography (CCTA) for the diagnosis and treatment of cardiovascular disease (CVD). We retrospectively identified CCTA data obtained between May 2008 and July 2018 in a multicenter (six centers) CVD study. The proposed method was evaluated on 422 patients' data by two studies. The first overall study involves training model on CVD patients and testing on non-CVD patients, as well as training on non-CVD patients and testing on CVD patients. The second study was performed using the leave-center-out approach. The method performance was evaluated using Dice similarity coefficient (DSC), Jaccard index (JAC), 95% Hausdorff distance (HD95), mean surface distance (MSD), residual mean square distance (RMSD), and the center of mass distance (CMD). The robustness of the proposed method was tested using the nonparametric Kruskal-Wallis test and post hoc test to assess the equality of distribution of DSC values among different tests. The automatic segmentation achieved a strong correlation with contour (ICC and R > 0.97, p value < 0.001 throughout all tests). The accuracy of the proposed method remained hi...Continue Reading

References

Jun 11, 2002·Obesity Research·Lelio MorriconeFrancesco Caviezel
Oct 13, 2004·The American Journal of Cardiology·Gianluca IacobellisFrida Leonetti
Jun 2, 2007·American Heart Journal·Harold S Sacks, John N Fain
Sep 9, 2008·The American Journal of Cardiology·Sanjay SarinJamshid Shirani
Feb 21, 2009·Arteriosclerosis, Thrombosis, and Vascular Biology·Martin GreifAlexander W Leber
Jul 3, 2009·The American Journal of Clinical Nutrition·Jingzhong DingJ Jeffrey Carr
Aug 28, 2012·JAMA : the Journal of the American Medical Association·James K MinLaura Mauri
Oct 31, 2012·Cardiovascular Intervention and Therapeutics·Sadako MotoyamaYukio Ozaki
Mar 26, 2013·Current Cardiovascular Imaging Reports·Alan C KwanDavid A Bluemke
Jun 8, 2013·IEEE Transactions on Medical Imaging·Robin WolzDaniel Rueckert
Feb 18, 2017·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Bradley J EricksonTimothy L Kline
May 15, 2018·Journal of Cardiovascular Computed Tomography·Gurpreet SinghJames K Min
Jul 12, 2018·IEEE Transactions on Medical Imaging·Frederic CommandeurDamini Dey
Aug 28, 2018·The New England Journal of Medicine·UNKNOWN SCOT-HEART InvestigatorsMichelle C Williams
Oct 23, 2018·IEEE Transactions on Bio-medical Engineering·Deepak MishraArvinder Singh Soin
Feb 26, 2019·Medical Image Analysis·Jo SchlemperDaniel Rueckert
Oct 22, 2019·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Xue DongXiaofeng Yang
Feb 25, 2020·Radiology. Artificial Intelligence·Frederic CommandeurDamini Dey

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.