Automatic vs. Manual Detection of High Frequency Oscillations in Intracranial Recordings From the Human Temporal Lobe

Frontiers in Neurology
Aljoscha ThomschewskiYvonne Höller

Abstract

Background: High frequency oscillations (HFOs) have attracted great interest among neuroscientists and epileptologists in recent years. Not only has their occurrence been linked to epileptogenesis, but also to physiologic processes, such as memory consolidation. There are at least two big challenges for HFO research. First, detection, when performed manually, is time consuming and prone to rater biases, but when performed automatically, it is biased by artifacts mimicking HFOs. Second, distinguishing physiologic from pathologic HFOs in patients with epilepsy is problematic. Here we automatically and manually detected HFOs in intracranial EEGs (iEEG) of patients with epilepsy, recorded during a visual memory task in order to assess the feasibility of the different detection approaches to identify task-related ripples, supporting the physiologic nature of HFOs in the temporal lobe. Methods: Ten patients with unclear seizure origin and bilaterally implanted macroelectrodes took part in a visual memory consolidation task. In addition to iEEG, scalp EEG, electrooculography (EOG), and facial electromyography (EMG) were recorded. iEEG channels contralateral to the suspected epileptogenic zone were inspected visually for HFOs. Furtherm...Continue Reading

References

Feb 1, 1992·Electroencephalography and Clinical Neurophysiology·P J AllenS J Smith
Jul 1, 1992·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·R S FisherS Uematsu
Jul 29, 1994·Science·M A Wilson, B L McNaughton
May 5, 1999·Hippocampus·A BraginG Buzsáki
Feb 11, 2003·Proceedings of the National Academy of Sciences of the United States of America·Anton SirotaGyörgy Buzsáki
Jul 6, 2004·Annals of Neurology·Richard J StabaJerome Engel
Apr 25, 2006·Brain : a Journal of Neurology·J D JirschJ Gotman
Dec 19, 2006·Nature Neuroscience·Daoyun Ji, Matthew A Wilson
Jul 7, 2007·Brain : a Journal of Neurology·Zsófia ClemensJan Born
Jul 13, 2007·Brain : a Journal of Neurology·Elena UrrestarazuJean Gotman
Nov 15, 2007·Proceedings of the National Academy of Sciences of the United States of America·Steffen GaisPhilippe Peigneux
Feb 22, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Hiroshi OtsuboElizabeth J Donner
May 10, 2008·Neuron·Shlomit Yuval-GreenbergLeon Y Deouell
May 27, 2008·Brain : a Journal of Neurology·Nikolai AxmacherJuergen Fell
Jul 7, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Rina ZelmannJean Gotman
Aug 28, 2009·Neuron·Thomas J DavidsonMatthew A Wilson
Dec 4, 2009·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·C G BénarF Wendling
Aug 11, 2010·NeuroImage·Christopher K KovachRalph Adolphs
Jul 19, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·R ZelmannJ Gotman
Sep 24, 2011·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Nicolás von EllenriederJean Gotman
Mar 17, 2012·Progress in Neurobiology·G A WorrellM Le Van Quyen
Mar 28, 2012·Progress in Neurobiology·György Buzsáki, Fernando Lopes da Silva
Apr 5, 2012·Epilepsy Currents·Gregory Worrell
Apr 7, 2012·Progress in Neurobiology·J JacobsJ Gotman
Jun 24, 2015·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Mina AmiriJean Gotman
Feb 6, 2017·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Aaron M SpringPaolo Federico
Feb 27, 2017·Journal of Physiology, Paris·Miguel NavarreteMichel Le Van Quyen
Mar 23, 2017·Journal of Neural Engineering·Carolina MigliorelliMiguel A Mañanas
Jun 18, 2017·Epilepsia·Maeike ZijlmansMichel Le Van Quyen
Jul 1, 2017·Epilepsia·Birgit FrauscherJean Gotman
Jul 4, 2017·International Journal of Neural Systems·Guo-Ping RenXiao-Feng Yang
Nov 9, 2017·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Shoichi ShimamotoShennan A Weiss

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