Autonomic control of heart rate after brain injury in children

Critical Care Medicine
B GoldsteinP D Woolf

Abstract

To study sequential changes in heart rate, respiratory rate, blood pressure, heart rate power spectra, and plasma catecholamine concentrations in patients with acute brain injury and correlate these variables with the severity of neurologic dysfunction and patient outcome. Prospective, clinical study. Pediatric intensive care unit. Thirty-seven pediatric patients with acute brain injury caused by trauma, anoxia/ischemia, hemorrhage, or infection. None. We found significant associations between low-frequency (0.01 to 0.15 Hz) heart rate power and severity of neurologic dysfunction (as assessed by the admission Glasgow Coma Scale) (p < .001) and patient outcome (as assessed by the Glasgow Outcome Scale) (p = .05). The admission (p = .05) and maximum (p < .001) values for low-frequency heart rate power and the minimum value for high-frequency (0.15 to 0.50 Hz) heart rate power obtained during hospitalization (p = .001) predicted an increased likelihood of survival. Ten brain-dead patients had significantly decreased low-frequency heart rate power (p = .008) and plasma norepinephrine (p = .015), epinephrine (p = .03), and dopamine (p = .04) concentrations when compared with six non-brain-dead patients with a Glasgow Coma Scale scor...Continue Reading

References

Mar 1, 1992·Critical Care Medicine·J KärkeläA Harmoinen
Mar 1, 1991·The American Journal of Physiology·Y Inoue, N Sperelakis
Apr 1, 1990·The American Journal of Physiology·S W ChaeC O Lee
Oct 1, 1988·American Journal of Diseases of Children·H HennesJ Losek
Jun 1, 1987·Journal of Neurosurgery·P D WoolfJ V McDonald
May 1, 1987·Annals of Neurology·R W HamillM Kelly
Sep 1, 1986·Neurosurgery·T J Leipzig, R I Lowensohn
Nov 1, 1971·The American Journal of Physiology·I NinomiyaH Irisawa
Sep 1, 1965·The American Journal of Cardiology·C VallbonaH E Hoff
Jul 1, 1994·Pediatric Research·M J Schlesinger
Feb 1, 1993·Critical Care Medicine·B GoldsteinP D Woolf

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Citations

Jul 13, 2000·Critical Care Medicine·D ToweillB Goldstein
Jan 12, 2001·Critical Care Medicine·A K BiswasP M Luckett
Jan 12, 2001·Critical Care Medicine·B Goldstein, M S Ellenby
Dec 24, 2005·Critical Care Medicine·Roberto HorneroBrahm Goldstein
Oct 11, 2005·Pediatric Emergency Care·Durgul OzdemirSevket Tektas
Nov 14, 2006·The Journal of Trauma·Juan Francisco Fernández-OrtegaGuillermo Quesada-García
Jul 12, 2007·The Journal of Trauma·Kenneth G ProctorRobert C Duncan
Dec 13, 2007·The Journal of Trauma·William P RiordanJohn A Morris
Oct 19, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·F ConciP Castiglioni
Nov 16, 2013·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Simone HoegerBenito A Yard
Feb 24, 2012·Indian Journal of Pediatrics·Didem AliefendioğluCihat Sanlı
Dec 17, 2015·Brain Injury : [BI]·Tracy A BlakeCarolyn A Emery
Jul 21, 2015·The Journal of Surgical Research·Jason S MurryEric J Ley
May 8, 2007·Journal of the American College of Surgeons·John A MorrisJudith M Jenkins
Jun 11, 2011·Acta Anaesthesiologica Scandinavica·Anna Teresa MazzeoL B Santamaria
Dec 27, 2005·Progress in Neurobiology·Julie Y H ChanSamuel H H Chan
Oct 28, 2005·Advances in Surgery·John A Morris, Patrick R Norris
Jun 28, 2005·The Journal of Surgical Research·Patrick R NorrisAnna E Williams
Jul 30, 2014·The American Journal of Emergency Medicine·Samantha W Gee, Todd J Karsies
Nov 4, 2010·The Journal of Trauma·Daithi S HeffernanBryan A Cotton
Jun 27, 2001·Journal of Neurosurgical Anesthesiology·T RapenneM Freysz
Oct 3, 2002·Current Opinion in Critical Care·Yi Gang, Marek Malik
Feb 6, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·John L DobsonThomas Buckley
Jul 8, 2015·The Journal of Trauma and Acute Care Surgery·Alison R GardnerJohn Petty
Oct 16, 2018·Frontiers in Neurology·Christopher MelinoskyNeeraj Badjatia
Sep 29, 2019·Frontiers in Neuroendocrinology·Zachary M Weil, Kate Karelina
Nov 17, 2020·Brain Injury : [BI]·Marta João Silva, Natália Antunes
Oct 2, 1998·The American Journal of Physiology·B GoldsteinB Kimberly

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Brain Injury & Trauma

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