Autonomic dysfunctions in patients with inflammatory bowel disease in clinical remission.

Digestive Diseases and Sciences
Purnima SharmaKishore Kumar Deepak

Abstract

The autonomic nervous system, especially the parasympathetic system, has been reported to modulate the immune response in chronic inflammatory disorders. Autonomic dysfunctions have been reported earlier in patients with inflammatory bowel disease; however, the results have been conflicting. We therefore evaluated autonomic functions in patients with inflammatory bowel disease (IBD) in clinical remission. Heart rate variability, a marker of autonomic functions, which included time-domain, frequency-domain, and nonlinear indices (Poincaré plot) was assessed using Nevrokard, version 6.4.0 Slovenia, in 118 patients with IBD (ulcerative colitis [UC] 62, and Crohn's disease [CD] 56) and 58 healthy controls. There was no difference in mean of R-R intervals in patients with UC, CD, and healthy controls. Frequency domain indices (absolute values of total power, high-frequency power, and low-frequency power) were lower in patients with UC and CD vs. healthy controls. High-frequency (HFnu) (expressed in normalized units) was significantly lower in UC compared to healthy controls. There was no significant difference in the low-frequency (LFnu) and LF/HF ratio in UC, CD, and healthy controls. Amongst the Poincaré plot indices, while standa...Continue Reading

References

Jan 1, 1977·Scandinavian Journal of Gastroenterology·K KyösolaM Salaspuro
Jan 23, 1999·European Journal of Gastroenterology & Hepatology·R EliakimA Fich
Nov 21, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·K MatsunagaY Yamamoto
Dec 26, 2001·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·A DruschkyB Neundörfer
Mar 20, 2002·The Journal of Experimental Medicine·Thomas R BernikKevin J Tracey
Dec 20, 2002·Nature·Kevin J Tracey
Jan 28, 2003·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·I A MouzasE A Kouroumalis
Oct 29, 1955·British Medical Journal·S C TRUELOVE, L J WITTS
Oct 3, 2003·Rheumatology International·Harun EvrengülMustafa Kilic
Mar 5, 2004·International Journal of Cardiology·Chander Mohan MittalK K Deepak
Aug 27, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Raffaello FurlanAlberto Malliani
Jun 19, 2007·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Simona MaulePietro Cortelli
Aug 4, 2007·American Journal of Physiology. Gastrointestinal and Liver Physiology·Jean-Eric GhiaStephen M Collins
Aug 19, 2007·BMC Gastroenterology·Bodil OhlssonStefan Lindgren
Oct 13, 2007·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·S C GanguliG Tougas
Nov 27, 2007·European Journal of Clinical Investigation·P CoruzziF Di Mario
Mar 7, 2008·World Journal of Gastroenterology : WJG·Jaya BenjaminYogendra K Joshi

❮ Previous
Next ❯

Citations

May 27, 2010·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·L Benavente, G Morís
Oct 1, 2011·International Journal of Medical Sciences·Yuksel DoganIsa Sevindir
Jan 15, 2014·Autonomic Neuroscience : Basic & Clinical·Andrea L CerviAlan E Lomax
May 14, 2014·Digestive Diseases and Sciences·Luyao ZhangJieshou Li
Oct 9, 2015·Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi·Purnima SharmaKishore Kumar Deepak
Jun 26, 2012·Immunological Reviews·Peder S OlofssonKevin J Tracey
Jul 28, 2015·European Journal of Internal Medicine·Carmen García-Cabo, Germán Morís
Apr 14, 2015·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Aiping BaiYuan Guo
Dec 8, 2014·Best Practice & Research. Clinical Rheumatology·F A KoopmanP P Tak
May 27, 2017·Journal of Internal Medicine·F A KoopmanP P Tak
Oct 26, 2013·Toxicologic Pathology·Derek M MoynesAlan E Lomax
Feb 9, 2016·World Journal of Gastrointestinal Pharmacology and Therapeutics·Carlos TeruelFrancisco Mesonero
Jul 9, 2014·Nature Reviews. Gastroenterology & Hepatology·Stuart M Brierley, David R Linden
Sep 3, 2010·The Journal of Rheumatology·Oskar HammarThomas Mandl
Feb 27, 2020·Circulation Journal : Official Journal of the Japanese Circulation Society·Monika GawałkoJędrzej Kosiuk
Feb 1, 2019·Terapevticheskiĭ arkhiv·I V MaevD N Andreev
Nov 12, 2019·Frontiers in Pediatrics·Yue SunHailong Cao
Jun 1, 2018·Inflammatory Bowel Diseases·Jessica Elia, Sunanda Kane
May 27, 2010·American Journal of Physiology. Gastrointestinal and Liver Physiology·Jutta KellerPeter Layer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society
S C GanguliG Tougas
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
Raffaello FurlanAlberto Malliani
© 2022 Meta ULC. All rights reserved