Autonomic dysregulation in burnout and depression: evidence for the central role of exhaustion

Scandinavian Journal of Work, Environment & Health
Magdalena K KanthakClemens Kirschbaum

Abstract

Objectives Given the important role of the autonomic nervous system (ANS) in stress regulation, astonishingly little is known about ANS functioning in burnout, a condition arising after prolonged exposure to work-related stress. The current study sought to investigate ANS modulation, as indexed by vagally-mediated heart rate variability (HRV), in relation to burnout symptomatology to (i) distinguish associations between the three dimensions of burnout [emotional exhaustion (EE), cynicism, reduced personal accomplishment] and (ii) investigate overlap in associations with depressive symptomatology. Methods Assessments of vagally-mediated HRV (ie, root mean square of successive differences, RMSSD) were conducted in a large population-based sample from the Dresden Burnout Study [N=410, mean age 42.2, standard deviation (SD) 11.2 years; 33.4% male]. Vagally-mediated HRV was assessed for 90 seconds during an emotionally-arousing situation (venipuncture, recumbent), a 335-second recumbent recovery period, and a 335-second seated resting condition. Results Results from multiple linear regression analyses revealed that EE was negatively related to RMSSD during venipuncture (=β -0.11, P=0.03) and the seated rest (β= -0.09, P=0.04) even a...Continue Reading

Citations

Feb 1, 2018·Stress : the International Journal on the Biology of Stress·Ross W MayFrank D Fincham
Apr 4, 2018·International Journal of Methods in Psychiatric Research·Marlene PenzClemens Kirschbaum
Mar 15, 2020·International Archives of Occupational and Environmental Health·Johannes WendscheMatthias Kliegel
Jun 12, 2018·Stress : the International Journal on the Biology of Stress·Magdalena Katharina WekenborgClemens Kirschbaum
Nov 7, 2019·Current Psychiatry Reports·Briana N BrownlowLaBarron K Hill
Sep 3, 2019·Frontiers in Psychology·Michael S Chin, Stefanos N Kales
Jul 1, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Evelina De LongisCristina Ottaviani
Oct 9, 2019·Psychosomatic Medicine·Magdalena K WekenborgClemens Kirschbaum
Apr 4, 2021·International Journal of Environmental Research and Public Health·Yunke ShiJian Li
Oct 17, 2017·Psychoneuroendocrinology·Natalie Urfer-MaurerSakari Lemola
May 18, 2021·The Journal of the American Academy of Orthopaedic Surgeons·David S JevsevarPaul M Werth

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