Autonomic regulation in asthmatics with gastroesophageal reflux

Chest
U LodiL H Walker

Abstract

To study the role of autonomic regulation in asthmatics with gastroesophageal reflux (GER). Prospective study. Autonomic function laboratory of a 908-bed university hospital. Fifteen nonsmoking asthmatics with GER (six men, nine women; average age, 36 years). Subjects were connected to an ECG monitor. BP was measured by sphygmomanometer at set intervals. After a resting period, each subject had heart rate and BP monitored during an 80 degrees passive tilt, Valsalva maneuver, quiet and deep breathing, handgrip, and an echo stress test of cortical arousal. Each autonomic function test was analyzed and defined as normal, hypervagal, hyperadrenergic, or mixed (a combination of hypervagal and hyperadrenergic responses) as compared with 23 age-matched normal control subjects from our laboratory (14 men, 9 women; average age, 35 years) and published normal control values. Each subject had an overall response score that was determined by the results of the tilt, Valsalva maneuver, and deep breathing maneuvers. All asthmatics with reflux had at least one autonomic function test display a hypervagal response. Overall response scores show that eight of 15 asthmatics with GER had an overall hypervagal response, and seven had a mixed respon...Continue Reading

Associated Clinical Trials

Sep 26, 2019·Rehab Abdelale Mohammed

References

Dec 6, 1976·JAMA : the Journal of the American Medical Association·E E Mays
Jul 1, 1992·Gut·S J SontagL Brand
Nov 1, 1991·The American Review of Respiratory Disease·P J BarnesM G Belvisi
Dec 1, 1991·The American Review of Respiratory Disease·P J BarnesM G Belvisi
Jan 1, 1971·The American Review of Respiratory Disease·J F MorrisL C Johnson
Mar 1, 1982·Annals of Internal Medicine·M KalinerJ C Venter

❮ Previous
Next ❯

Citations

Jan 15, 2004·American Journal of Respiratory Medicine : Drugs, Devices, and Other Interventions·Demetrios S TheodoropoulosStilianos E Efstratiadis
Jan 15, 2004·American Journal of Respiratory Medicine : Drugs, Devices, and Other Interventions·Babak Mokhlesi
Aug 21, 2003·The American Journal of Medicine·Mark R Stein
Mar 16, 2000·The American Journal of Medicine·J E Richter
Mar 1, 2000·Gastroenterology Clinics of North America·M B Fennerty
Mar 1, 2000·Gastroenterology Clinics of North America·S R OrensteinS Khan
Jan 15, 2002·Chest Surgery Clinics of North America·G Tougas, M Banemai
Sep 2, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·B M BalsonS J McGeady
Jan 9, 2004·Current Opinion in Otolaryngology & Head and Neck Surgery·Todd A Loehrl, Timothy L Smith
May 17, 2000·Current Opinion in Pulmonary Medicine·P E Patterson, S M Harding
Apr 29, 2005·International Journal of Clinical Practice·P Malfertheiner, B Hallerbäck
Jan 5, 2000·American Journal of Respiratory and Critical Care Medicine·G CuttittaG Bonsignore
Oct 13, 2012·BMC Gastroenterology·D Lakmali AmarasiriH Janaka de Silva
Oct 24, 2009·The Tohoku Journal of Experimental Medicine·Emre TascilarAyhan Kilic
Jun 28, 2005·Paediatric Drugs·Mark D ScarupaBrendan J Canning
Mar 31, 2010·Annals of Thoracic Medicine·Radhakrishna PanickerSeham Ahmed Ali
Nov 18, 2000·The Laryngoscope·S S JaradehR J Toohill
Feb 18, 2006·Minerva gastroenterologica e dietologica·A J P M Smout
Sep 15, 2015·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Shelka Dua, Latika Mohan
Oct 8, 1999·Chronobiology International·S M Harding
Sep 18, 2012·Otolaryngologic Clinics of North America·Michael Lupa, John M DelGaudio
Nov 22, 2011·Facial Plastic Surgery Clinics of North America·Todd A Loehrl
Jun 4, 2011·The Journal of Allergy and Clinical Immunology·Mario CastroUNKNOWN National Heart, Lung, and Blood Institute's Severe Asthma Research Program
Feb 23, 2010·Otolaryngologic Clinics of North America·John H Krouse, Kenneth W Altman
Nov 13, 2009·Medical Hypotheses·Nestor A Molfino
Dec 26, 2001·The American Journal of Medicine·S M Harding
Dec 26, 2001·The American Journal of Medicine·F Cibella, G Cuttitta
Jun 15, 2015·Revue des maladies respiratoires·S DirouF-X Blanc
Apr 28, 2012·The Laryngoscope·Todd A LoehrlNikki Johnston
Nov 27, 2004·Pulmonary Pharmacology & Therapeutics·Alvin J Ing
Jan 26, 2006·The Journal of Thoracic and Cardiovascular Surgery·Philip A LindenRaphael Bueno
Oct 4, 2005·European Journal of Internal Medicine·Doron Zamir
Dec 8, 2004·Immunology and Allergy Clinics of North America·Susan M Harding
Feb 16, 2002·The Annals of Thoracic Surgery·Kevin L GreasonPeter C Pairolero
Sep 18, 2010·The Journal of Medical Investigation : JMI·Masanari WatanabeEiji Shimizu
Jan 31, 2003·Respiratory Medicine·A RoussosN Philippou
Jul 30, 2016·Brazilian Journal of Otorhinolaryngology·Guilherme Constante Preis SellaFabiana Cardoso Pereira Valera
Oct 31, 2006·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·J K Dibaise, V K Sharma
May 9, 2002·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Todd A LoehrlSafwan S Jaradeh
Dec 2, 2017·Alimentary Pharmacology & Therapeutics·C BroersA Pauwels

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Antifungals (ASM)

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.

Antifungals

An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.