Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides

Current Opinion in Cell Biology
Siew Cheng PhuaTakanari Inoue

Abstract

The primary cilium is a cell surface projection from plasma membrane which transduces external stimuli to diverse signaling pathways. To function as an independent signaling organelle, the molecular composition of the ciliary membrane has to be distinct from that of the plasma membrane. Here, we review recent findings which have deepened our understanding of the unique yet dynamic phosphoinositide profile found in the primary cilia.

Citations

May 3, 2018·Essays in Biochemistry·Juan Wang, Maureen M Barr
Mar 20, 2019·Frontiers in Psychiatry·Michal Pruski, Bing Lang
May 31, 2019·Proceedings of the National Academy of Sciences of the United States of America·Jason Y JiangAldebaran M Hofer
May 28, 2019·Andrology·Laura GirardetClémence Belleannée
Apr 8, 2020·Cells·Theodore G Wensel
Apr 30, 2019·Frontiers in Immunology·Christian M Gawden-Bone, Gillian M Griffiths
Jun 17, 2020·Journal of Lipid Research·Raju V S Rajala
Feb 9, 2021·Journal of Lipid Research·Raju V S Rajala

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