Autophagy Is a Promoter for Aerobic Exercise Performance during High Altitude Training

Oxidative Medicine and Cellular Longevity
Ying Zhang, Ning Chen

Abstract

High altitude training is one of the effective strategies for improving aerobic exercise performance at sea level via altitude acclimatization, thereby improving oxygen transport and/or utilization. But its underlying molecular mechanisms on physiological functions and exercise performance of athletes are still vague. More recent evidence suggests that the recycling of cellular components by autophagy is an important process of the body involved in the adaptive responses to exercise. Whether high altitude training can activate autophagy or whether high altitude training can improve exercise performance through exercise-induced autophagy is still unclear. In this narrative review article, we will summarize current research advances in the improvement of exercise performance through high altitude training and its reasonable molecular mechanisms associated with autophagy, which will provide a new field to explore the molecular mechanisms of adaptive response to high altitude training.

References

Mar 11, 1977·Pflügers Archiv : European journal of physiology·J KasalickýJ Procházka
Jan 1, 1966·Annual Review of Physiology·C De Duve, R Wattiaux
Jan 1, 1984·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·A Salminen, V Vihko
Feb 15, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·F FavretN C Gonzalez
May 29, 2001·Current Medicinal Chemistry·C Leeuwenburgh, J W Heinecke
Apr 13, 2002·Advances in Experimental Medicine and Biology·H Hoppeler, M Vogt
Apr 16, 2002·Science·Hai WuR Sanders Williams
Dec 10, 2002·Medicine and Science in Sports and Exercise·Walter SchmidtJoseph Keul
Jul 16, 2003·Pflügers Archiv : European journal of physiology·B FriedmannR Billeter
Aug 1, 1960·Annals of Internal Medicine·A HURTADO
Oct 17, 2003·The Journal of Physiology·Julio F Turrens
Mar 18, 2004·American Journal of Physiology. Endocrinology and Metabolism·Taro ToyodaKazuwa Nakao
May 18, 2005·Seminars in Cell & Developmental Biology·Bradly G WoutersConstantinos Koumenis
Jul 26, 2005·Trends in Cardiovascular Medicine·Lawrence H YoungRaymond R Russell
Sep 28, 2005·High Altitude Medicine & Biology·Li-Ling ChiuChia-Hua Kuo
Feb 9, 2006·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Maria del Pilar ValleEmilio A Marticorena
Apr 29, 2006·The Journal of Physiology·D Grahame HardieJohn W Scott
May 13, 2006·The Journal of Physiology·Jason R B Dyck, Gary D Lopaschuk
May 26, 2006·Nature·Jacques PouysségurNathalie M Mazure
Jun 21, 2006·European Journal of Applied Physiology·Paul RobachJean-Paul Richalet
Jul 29, 2006·Autophagy·Sara Rodriguez-EnriquezJohn J Lemasters
May 15, 2007·Trends in Endocrinology and Metabolism : TEM·Irini ManoliGeorge P Chrousos
Jun 28, 2007·The Journal of Biological Chemistry·Edmond Y W ChanSharon A Tooze
Jul 6, 2007·Autophagy·Noboru Mizushima, Tamotsu Yoshimori
Sep 1, 2007·The Journal of Physiology·M Faadiel Essop
Oct 25, 2007·Biochemical Society Transactions·M G MackenzieK Baar
Jan 15, 2008·Free Radical Biology & Medicine·Scott K PowersAndreas N Kavazis
Feb 19, 2008·The Journal of Biological Chemistry·Huafeng ZhangGregg L Semenza
Mar 28, 2008·Autophagy·Junichi Sadoshima
Apr 29, 2008·Molecular Cell·Dana M GwinnReuben J Shaw
Nov 6, 2008·Experimental Gerontology·Christine Le PageSophie Besse
Nov 19, 2008·The Journal of Physiology·Matthew G MacKenzieKeith Baar
Nov 26, 2008·The Journal of Cell Biology·Derek NarendraRichard J Youle
Dec 9, 2008·The Biochemical Journal·Michael P Murphy

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gene knockout

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