PMID: 9544224Apr 17, 1998Paper

Autopsy in children with cancer who die while in terminal care

Medical and Pediatric Oncology
K SirkiäH Sariola

Abstract

The purpose of this study was to find out whether autopsy of children with cancer should be recommended after terminal care, or whether in those circumstances it could be abandoned. One hundred pediatric patients with cancer treated at the Children's Hospital, University of Helsinki, Finland, died during 1987-92. Seventy children died while in organized terminal care. The underlying diagnoses were brain tumors (21), other solid tumors (24), and leukemias (25). The method was a retrospective analysis of patients' records and autopsy reports, in addition to a structured interview of the two parents separately. Autopsy was performed in 40 (57%) of these 70 cases. It was more often performed on children dying in hospital (69%) than in those dying at home (39%). The autopsy rate also varied with the underlying disease: 68% of patients with leukemia, 50% of those with solid tumors, and 52% of those with brain tumors were autopsied. Autopsy afforded totally new medical information in 20% of cases, and important additional information in 55%. Nothing unexpected was found in 25%. Almost all the parents (94%) who agreed to autopsy felt that it was appropriate. Of both mothers and fathers, 50% felt that knowing the findings at autopsy was...Continue Reading

References

Apr 1, 1992·The Journal of Pathology·C ChampS B Coghill
Jun 1, 1990·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·B KarwinskiF Hartveit
Dec 1, 1980·The Journal of Pediatrics·M E Lauer, B M Camitta
Apr 1, 1995·Histopathology·I B ScheimbergJ D van der Walt
Mar 1, 1995·Human Pathology·V de Pangher ManziniA Brollo
Jan 1, 1994·The Journal of Pathology·R D StartW K Cotton
Dec 1, 1993·Quality Assurance in Health Care : the Official Journal of the International Society for Quality Assurance in Health Care·I Hägerstrand, L M Lundberg
Dec 1, 1993·Quality Assurance in Health Care : the Official Journal of the International Society for Quality Assurance in Health Care·C N Petri
Feb 1, 1993·Human Pathology·V R SarodeB D Radotra

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Citations

Jun 23, 2001·Archives of Disease in Childhood. Fetal and Neonatal Edition·H E McHaffieA J Lyon
Oct 31, 2012·Pediatric Blood & Cancer·Jason A Jarzembowski, M John Hicks
Feb 13, 2017·BJOG : an International Journal of Obstetrics and Gynaecology·C LewisN J Sebire
Sep 7, 2006·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Tyler BucknerScott Victor Smith
May 18, 2010·Journal of Neuro-oncology·Paola AngeliniUte Bartels
Mar 7, 2002·Journal of Pediatric Hematology/oncology·K J KlopfensteinF B Ruymann
Mar 7, 2002·Journal of Pediatric Hematology/oncology·W S Ferguson
Apr 17, 1998·Medical and Pediatric Oncology·M H Collins
Jun 2, 2005·La Revue de médecine interne·B Pasquier
Jun 5, 2001·Pediatrics·M H CollinsJ E Tomaszewski

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