PMID: 11912069Mar 26, 2002Paper

Autoshaping of ethanol drinking: an animal model of binge drinking

Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism
A TomieL A Pohorecky

Abstract

To examine the hypothesis that Pavlovian autoshaping provides an animal learning model of drug abuse, two studies evaluated the induction of ethanol drinking by autoshaping procedures. In Experiment 1, the sipper tube conditioned stimulus (CS) contained saccharin/ethanol solution and was repeatedly paired with food as an unconditioned stimulus (US). The CS-US paired group consumed more of the 0.1% saccharin-6% ethanol solution than did the CS-US random group, revealing that autoshaping conditioned responses (CR) induce ethanol drinking not attributable to pseudo-conditioning. Experiment 2 employed saccharin-fading procedures and showed that the paired vs random group differences in ethanol drinking were maintained, even as the saccharin was eliminated from the solution. The results show that Pavlovian autoshaping procedures induce high volumes of ethanol drinking when the presentation of a sipper tube containing an ethanol solution precedes the response-independent delivery of food. The high volume of ethanol consumed in a brief period of time suggests that Pavlovian autoshaping may be a model of binge drinking.

Citations

Jun 9, 2006·Addiction Biology·Carla Sanchis-Segura, Rainer Spanagel
Sep 12, 2006·Addiction Biology·John C CrabbeGeorge F Koob
Apr 14, 2005·Learning & Behavior·David N Kearns, Stanley J Weiss
Jun 15, 2007·Substance Use & Misuse·David B Newlin, Kevin A Strubler
Dec 24, 2003·Alcoholism, Clinical and Experimental Research·Andrea M AllanKevin K Caldwell
Aug 2, 2008·Alcoholism, Clinical and Experimental Research·Jeffrey A SimmsSelena E Bartlett
Mar 24, 2006·The European Journal of Neuroscience·Jeremy J DayRegina M Carelli
Jan 12, 2005·Physiology & Behavior·Justin S RhodesJohn C Crabbe
Dec 22, 2004·Progress in Neuro-psychopharmacology & Biological Psychiatry·Arthur TomieLarissa A Pohorecky
Apr 22, 2004·Pharmacology, Biochemistry, and Behavior·Arthur TomieLarissa A Pohorecky
Mar 19, 2015·Frontiers in Behavioral Neuroscience·Chandra S SreyNadia Chaudhri
Mar 2, 2011·Pharmacology, Biochemistry, and Behavior·Arthur TomieLarissa A Pohorecky
Jan 11, 2005·Behavioural Brain Research·Arthur TomieLarissa A Pohorecky
Jan 21, 2018·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Barry J EverittDavid Belin
May 23, 2020·Perspectives on Behavior Science·Stephanie P da Silva, April Michele Williams
Feb 16, 2006·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Arthur TomieLarissa A Pohorecky
Apr 14, 2021·Cognitive, Affective & Behavioral Neuroscience·M VigoritoA J Pra Sisto

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