PMID: 8607679Apr 1, 1996Paper

Autotransfusion after coronary artery bypass grafting halves the number of patients needing blood transfusion

The Annals of Thoracic Surgery
H SchmidtE A Jensen

Abstract

Several randomized studies about autotransfusion of shed mediastinal blood in patients undergoing coronary artery bypass grafting have resulted in divergent findings concerning reduction of the need for homologous blood transfusions. Most of these studies used less strict criteria for homologous blood transfusion than applied in daily clinical practice. A prospective, randomized, controlled study involving 120 patients having elective, uncomplicated coronary artery bypass grafting was performed. The autotransfusion group received transfusion of shed mediastinal blood for 18 hours. Criteria for homologous blood transfusion were hemoglobin concentration less than 5.0 mmol/L in the intensive care unit and less than 5.5 mmol/L during the rest of the hospital stay. Twenty-eight percent of patients in the autotransfusion group received homologous blood transfusion versus 55% in the control group (p = 0.007). Ninety-five percent of the shed mediastinal blood was transfused. In the autotransfusion group, a total of 26 units of homologous blood was used versus 78 units in the control group (p < 0.001). Autotransfusion of shed mediastinal blood in patients undergoing elective, uncomplicated coronary artery bypass grafting halves the numb...Continue Reading

References

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Citations

Sep 2, 1998·The Annals of Thoracic Surgery·H K Kjaergard, H R Trumbull
Sep 23, 2003·The Journal of Thoracic and Cardiovascular Surgery·Michael K BanburyDelos M Cosgrove
Oct 6, 1997·Acta Anaesthesiologica Scandinavica·H SchmidtE Jensen
May 30, 1998·Acta Anaesthesiologica Scandinavica·H SchmidtP E Mortensen
Oct 18, 2011·Journal of Cardiothoracic and Vascular Anesthesia·Bhanu P NallaC David Mazer
May 4, 2000·Journal of Cardiothoracic and Vascular Anesthesia·M H ErethW C Oliver
Jul 1, 1996·The Annals of Thoracic Surgery·H SchmidtS L Nielsen
Oct 3, 1999·The Journal of Thoracic and Cardiovascular Surgery·H I Flom-HalvorsenR Oystese
Apr 28, 2004·The Annals of Thoracic Surgery·Gavin J MurphyMalcolm J R Dalrymple-Hay
May 1, 1997·The Annals of Thoracic Surgery·H SchmidtE A Jensen
Aug 30, 2000·The Journal of Thoracic and Cardiovascular Surgery·J MartinM Carrier
Sep 22, 2001·Perfusion·S J Morris

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