PMID: 9186831May 1, 1997Paper

Auxiliary partial orthotopic liver transplantation for acute liver failure

Journal of Hepatology
S P PereiraR Williams

Abstract

Auxiliary partial orthotopic liver transplantation holds potential advantages over conventional orthotopic liver transplantation, but experience with the technique in acute liver failure is limited. We describe our initial experience in seven patients (4 men, 3 women; mean age 28, range 14-35 years) with acute liver failure (paracetamol 3, non A-E 2, autoimmune 1, Ecstasy 1) who fulfilled criteria for emergency transplantation. Preoperatively, the median international normalised ratio was seven (range 3.4-15), with a creatinine of 123 microM (51-389 microM) and bilirubin 320 microM (61-572 microM). The reasons for performing an auxiliary transplant were the patients' young age and stable preoperative condition (n = 5), or a significant psychiatric history precluding conventional transplantation (n = 2). All patients received blood group-matched left (n = 2) or right (n = 5) auxiliary grafts. Median duration of surgery was 8.5 h (7.3-10 h), with blood loss of 8.3 litres (4.6-14.6 litres). Post-transplant, the international normalised ratio and aspartate aminotransferase fell progressively in all patients, with median values at day 7 of 1.4 (1.0-2.4) and 108 IU/1 (78-910 IU/1). Three patients died from sepsis within the first pos...Continue Reading

References

Apr 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H K Wolf, G K Michalopoulos
Aug 17, 1991·BMJ : British Medical Journal·C M FlorkowskiA F Jones
Feb 1, 1990·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Y ShiratoriT Sugimoto
Dec 8, 1988·The New England Journal of Medicine·O T TerpstraC B Reuvers
Jun 1, 1988·Transplantation·O T TerpstraS W Schalm
Jun 1, 1995·Clinical Transplantation·H C BodenheimerP Sheiner
Sep 25, 1993·Lancet·P F WhitingtonJ R Thistlethwaite
Apr 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J DevlinR Williams
Apr 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·D L LaskinD J Jollow
Jan 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J H HoofnagleN Ascher
Jan 27, 1995·Transplantation·K BoudjemaJ P Bellocq
Feb 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·C HanauR Rubin
Jan 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·F SchneiderJ D Tempé
Jul 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·R Williams, J Wendon
May 1, 1994·Artificial Organs·N L SussmanJ H Kelly
May 1, 1994·Seminars in Liver Disease·A L HoffmanL Makowka
Jul 31, 1993·Lancet·J G O'GradyR Williams
Jul 1, 1993·Annals of Surgery·B RingeR Pichlmayr
May 1, 1996·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M P Chenard-NeuJ P Bellocq
Nov 1, 1996·Seminars in Liver Disease·H BismuthS P Pereira
May 1, 1995·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·B W Shaw
Jan 1, 1996·Liver Transplantation and Surgery : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·J PitreY Chapuis

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Citations

Apr 16, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·W BernalR Williams
Apr 4, 2002·Indian Journal of Pediatrics·Mohamed Rela, Anil Dhawan
Jun 10, 2006·Journal of Inherited Metabolic Disease·Anil DhawanRobin D Hughes
May 28, 2005·Transplantation Proceedings·R GirlandaN D Heaton
Aug 11, 2001·Transplantation Proceedings·L De CarlisD Forti
Sep 2, 1998·Transplantation Proceedings·E AndornoU Valente
Nov 21, 2000·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·C MargaritE Murio
Jan 11, 2001·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·L M Petrovic
Sep 23, 2009·Current Opinion in Nephrology and Hypertension·Joo-Hee WaelzleinAnil Dhawan
May 7, 2009·World Journal of Gastroenterology : WJG·Giada PietrosiBruno Gridelli
Feb 13, 2016·Pediatric Radiology·Rama S AyyalaCarrie Ruzal-Shapiro
Mar 11, 2016·Indian Journal of Anaesthesia·Akila RajakumarMohamed Rela
Mar 12, 2008·HPB : the Official Journal of the International Hepato Pancreato Biliary Association·J BelghitiF Durand
Oct 20, 2015·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Joshua WeinerTomoaki Kato
Aug 30, 2005·Journal of the American College of Surgeons·Neal R BarshesSamir S Awad
Sep 29, 2007·Liver International : Official Journal of the International Association for the Study of the Liver·Nobito HiguchiMunechika Enjoji
Jul 1, 2016·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Mohamed RelaMettu Srinivas Reddy
Apr 16, 2003·Cell Transplantation·Ragai R MitryAnil Dhawan
Mar 4, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·M FujitaK Nagashima
Dec 24, 2018·Journal of Veterinary Internal Medicine·Peter H KookMaja Ruetten
Jun 8, 2021·Transplantation Reviews·Joana QuadrosMaria Francelina Lopes

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