Auxin regulates SNARE-dependent vacuolar morphology restricting cell size

ELife
Christian LöfkeJürgen Kleine-Vehn

Abstract

The control of cellular growth is central to multicellular patterning. In plants, the encapsulating cell wall literally binds neighbouring cells to each other and limits cellular sliding/migration. In contrast to its developmental importance, growth regulation is poorly understood in plants. Here, we reveal that the phytohormone auxin impacts on the shape of the biggest plant organelle, the vacuole. TIR1/AFBs-dependent auxin signalling posttranslationally controls the protein abundance of vacuolar SNARE components. Genetic and pharmacological interference with the auxin effect on vacuolar SNAREs interrelates with auxin-resistant vacuolar morphogenesis and cell size regulation. Vacuolar SNARE VTI11 is strictly required for auxin-reliant vacuolar morphogenesis and loss of function renders cells largely insensitive to auxin-dependent growth inhibition. Our data suggests that the adaptation of SNARE-dependent vacuolar morphogenesis allows auxin to limit cellular expansion, contributing to root organ growth rates.

References

Mar 17, 1998·Developmental Biology·F BergerJ Schiefelbein
Apr 24, 1999·The Plant Cell·F Marty
Mar 11, 2000·Molecular Biology of the Cell·A MayerA Haas
Jun 20, 2003·Proceedings of the National Academy of Sciences of the United States of America·Daisuke YanoMasao Tasaka
Mar 31, 2005·Current Biology : CB·Mitsuru NiihamaMiyo Terao Morita
May 27, 2005·Nature·Nihal DharmasiriMark Estelle
May 27, 2005·Nature·Stefan Kepinski, Ottoline Leyser
Jul 5, 2005·Developmental Cell·Nihal DharmasiriMark Estelle
Dec 1, 1986·Plant Physiology·R O Erickson
Jun 7, 2006·Current Biology : CB·Ottoline Leyser
Aug 1, 2006·Current Opinion in Plant Biology·Marcel Quint, William M Gray
May 23, 2008·Nature Reviews. Molecular Cell Biology·Sascha Martens, Harvey T McMahon
Jun 14, 2008·Proceedings of the National Academy of Sciences of the United States of America·Stéphanie RobertGlenn R Hicks
Jul 18, 2008·Annual Review of Cell and Developmental Biology·Keithanne Mockaitis, Mark Estelle
Mar 25, 2009·The Plant Journal : for Cell and Molecular Biology·Niko GeldnerJoanne Chory
Nov 26, 2010·The Plant Journal : for Cell and Molecular Biology·Tomohiro UemuraAkihiko Nakano
Jul 2, 2011·The Plant Cell·Michael Sauer, Jürgen Kleine-Vehn
Oct 26, 2011·Proceedings of the National Academy of Sciences of the United States of America·Kiyoshi MashiguchiHiroyuki Kasahara
Jan 12, 2012·ACS Chemical Biology·Ken-ichiro HayashiHiroshi Nozaki
Mar 13, 2012·Journal of Experimental Botany·Kisten Sisse Krag GjettingAnja Thoe Fuglsang
Jul 31, 2012·Current Biology : CB·Michael J DeeksPatrick J Hussey
Sep 18, 2012·Nature Cell Biology·Benjamin PéretMalcolm J Bennett
Apr 19, 2013·Frontiers in Plant Science·Gian-Pietro Di Sansebastiano
May 15, 2013·Journal of Experimental Botany·Michael SauerJürgen Kleine-Vehn
Feb 20, 2014·Proceedings of the National Academy of Sciences of the United States of America·Petra NovákováJirí Friml
Feb 27, 2014·Molecular Plant·Jiameng ZhengMarcela Rojas-Pierce
Nov 20, 2014·Methods in Molecular Biology·David ScheuringChristian Löfke

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Citations

Dec 31, 2015·Proceedings of the National Academy of Sciences of the United States of America·David ScheuringJürgen Kleine-Vehn
Sep 2, 2015·Proceedings of the National Academy of Sciences of the United States of America·Kamila KalinowskaErika Isono
Oct 12, 2015·Current Opinion in Plant Biology·Kai Dünser, Jürgen Kleine-Vehn
Jun 25, 2015·Frontiers in Plant Science·Pengwei Wang, Patrick J Hussey
Oct 11, 2016·Current Opinion in Plant Biology·Robert Sablowski
Dec 19, 2017·Plant Signaling & Behavior·Ayumi YamagamiTakeshi Nakano
Mar 7, 2019·Journal of Cell Science·Jonathan Michael DragwidgeAnthony Richard Gendall
Apr 8, 2016·Plant Molecular Biology·Victoria Naser, Eilon Shani
Apr 21, 2019·The New Phytologist·Rana MunnsStephen D Tyerman
May 23, 2020·Annual Review of Plant Biology·Lise C Noack, Yvon Jaillais
Mar 7, 2020·Annual Review of Plant Biology·Minmin DuWilliam M Gray
Nov 26, 2016·Bioscience, Biotechnology, and Biochemistry·Sayaka KimuraTakashi Iwasaki
May 28, 2020·Frontiers in Plant Science·Sabrina Kaiser, David Scheuring
Feb 9, 2019·Frontiers in Plant Science·M Victoria AlarcónPedro G Lloret
Sep 29, 2019·International Journal of Molecular Sciences·Sabrina KaiserDavid Scheuring
Apr 24, 2020·Proceedings of the National Academy of Sciences of the United States of America·María Otilia DelgadilloEnrique Rojo
Sep 5, 2018·Journal of Cell Science·Xingyun QiDaniël Van Damme
Feb 14, 2019·Proceedings of the National Academy of Sciences of the United States of America·Elena FeraruJürgen Kleine-Vehn
Aug 7, 2018·Frontiers in Plant Science·Fabrizio CartenìFrancesco Giannino
May 20, 2020·Frontiers in Plant Science·Judith García-GonzálezKateřina Schwarzerová
Oct 30, 2020·Evolutionary Bioinformatics Online·Xiaoyan GuKeith Lindsey
May 15, 2020·Trends in Plant Science·Yong CuiLiwen Jiang
Jan 13, 2021·Cold Spring Harbor Perspectives in Biology·Jorge J Casal, José M Estevez
May 4, 2021·Plant Signaling & Behavior·Sabrina KaiserDavid Scheuring
Jan 13, 2021·Cold Spring Harbor Perspectives in Biology·Ken-Ichiro Hayashi
Oct 12, 2021·The Plant Cell·Byung-Ho KangBethany Karlin Zolman

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Methods Mentioned

BETA
ubiquitination
genetic interference

Software Mentioned

Leica LAS AF
graphpad
imageJ

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