PMID: 8951435Nov 1, 1996Paper

Average spectrum of cochlear activity: a possible synchronized firing, its olivo-cochlear feedback and alterations under anesthesia

Hearing Research
Y Cazals, Z W Huang

Abstract

Average spectrum of electrophysiological cochlear activity (ASECA) recorded from the cochlea or the eighth nerve is related to firing of auditory neurons and has been used recently in search of an objective measure of tinnitus both in animal models and in humans. Little is known about neuro-sensory processes underlying the spectral features of ASECA. The present study used awake and/or anesthetized animals and investigated effects of various sounds presented contralaterally and ipsilaterally. Contralateral stimulation with noise bands at frequencies above about 8 kHz and below acoustic interaural cross-talk decreased the amplitude of the 1 kHz peak of ASECA. When presented ipsilaterally noises produced either an increase or a decrease of this spectral peak when the acoustic bandwidth was respectively above or below 1.5 kHz. Pure tones when presented contralaterally had no detectable effect. When presented ipsilaterally pure tones with frequencies higher than about 4 kHz decreased the 1 kHz peak of ASECA. The detailed time course of sound-induced variations of the 1 kHz peak was measured by time averaging. The resulting response patterns resemble PST histograms of the auditory nerve. Sedation and anesthesia deepened the 500 Hz t...Continue Reading

References

Jul 1, 1976·Biophysical Journal·D H Johnson, N Y Kiang
Mar 1, 1976·The Journal of the Acoustical Society of America·P Dallos, M A Cheatham
Nov 1, 1992·Hearing Research·E R Lewis, K R Henry
Nov 1, 1990·Hearing Research·N Y Kiang
Apr 1, 1990·The Journal of the Acoustical Society of America·D O KimJ G Sirianni
Jun 1, 1990·The Journal of the Acoustical Society of America·D F DolanG Avinash
Jan 1, 1986·Hearing Research·M C Liberman, M C Brown
Sep 1, 1984·Hearing Research·R L Snyder, C E Schreiner
May 1, 1983·The Journal of the Acoustical Society of America·M C BrownA L Nuttall
Jan 15, 1982·Science·S M Khanna, D G Leonard
Jul 1, 1982·The Journal of the Acoustical Society of America·P M SellickB M Johnstone
Oct 1, 1980·The Journal of the Acoustical Society of America·D H Johnson
Nov 17, 1995·Science·M MeisterD A Baylor
Jan 1, 1994·Hearing Research·R A VellutiP M Narins
Aug 1, 1993·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·J A Brien
Jun 1, 1993·The Laryngoscope·W H MartinM L Ronis

❮ Previous
Next ❯

Citations

Jun 5, 2003·Journal of the Association for Research in Otolaryngology : JARO·E Christopher Kirk, David W Smith
Apr 28, 2004·Hearing Research·Saida HadjabPhilippe Siaud
May 26, 2004·Hearing Research·G D SearchfieldP R Thorne
Jun 1, 2005·Hearing Research·W H A M Mulders, D Robertson
Jul 6, 2000·Progress in Neurobiology·Y Cazals
Apr 13, 2002·Hearing Research·Raymond D CookDebara L Tucci
Oct 10, 2002·Hearing Research·Catherine M McMahon, Robert B Patuzzi
Nov 16, 2002·Hearing Research·Fabrice GiraudetYves Cazals
Feb 3, 1998·Hearing Research·A L NuttallD F Dolan
Sep 28, 1998·The European Journal of Neuroscience·K C HornerY Cazals
Nov 16, 2013·Noise & Health·Jennifer CampoloRichard Salvi
Jun 17, 1998·Audiology : Official Organ of the International Society of Audiology·D Lima da CostaJ M Aran
Jan 5, 2002·Audiology : Official Organ of the International Society of Audiology·S G KorresG Adamopoulos
Sep 23, 2003·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Renaud MellerJacques Magnan
Sep 27, 2002·British Medical Bulletin·David M Baguley
Jan 18, 2018·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Bin YiHao Wu
Jun 15, 2004·Neuroreport·Matthieu J GuittonPierre Bonfils
Jul 27, 2017·Frontiers in Neuroscience·Javiera Pardo-JaduePaul H Delano
Aug 30, 2017·Molecular Medicine Reports·Xiang-Hong Chen, Li-Li Zheng
Aug 14, 2021·Frontiers in Cellular Neuroscience·Penelope W C JeffersSharon G Kujawa

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.