PMID: 6982181Jan 1, 1982Paper

Avian lymphokines: 1. Thymic cell growth factor in supernatants of mitogen stimulated chicken spleen cells

Developmental and Comparative Immunology
K SchauensteinG Wick

Abstract

The present study provides first evidence for the presence of a thymic cell growth factor (TCGF) in supernatants (20 hrs) of mitogen (Con A) stimulated chicken spleen cells. 2 out of 3 batches of supernatant prepared according to a procedure originally described for the mouse system (10) induced a vigorous proliferative response of Con A prestimulated chicken spleen cells without significant mitogenic effect on unstimulated lymphocytes. No crossreactivity of this chicken-TCGF was observed with prestimulated murine lymphocytes, nor did potent mouse-TCGF preparations exhibit any proliferative effect on chicken cells. The implications of these data for both phylogenetic as well as practical experimental aspects are discussed.

References

Mar 15, 1976·Cellular Immunology·D M Chen, G Di Sabato
Oct 1, 1978·The Journal of Experimental Medicine·S GillisK A Smith
Apr 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·K Rulon, D W Talmage
Jan 1, 1981·Journal of Immunological Methods·P J Spiess, S A Rosenberg
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Citations

Jan 1, 1985·Developmental and Comparative Immunology·D Watkins, N Cohen
Jan 1, 1990·Developmental and Comparative Immunology·P S Holt
Jan 1, 1991·Developmental and Comparative Immunology·T H Lee, C H Tempelis
Jan 1, 1996·Developmental and Comparative Immunology·T D Obranovich, R L Boyd
Mar 1, 1987·Veterinary Immunology and Immunopathology·H Weiler, V von Bülow
Sep 1, 1996·Veterinary Immunology and Immunopathology·T L PertileJ M Sharma
Mar 14, 2001·Developmental and Comparative Immunology·K C Klasing, R K Peng
Feb 26, 2000·Developmental and Comparative Immunology·C Siatskas, R Boyd
Dec 1, 1995·British Poultry Science·J M Trout, M M Mashaly
Sep 1, 1994·Avian Pathology : Journal of the W.V.P.A·F McNeillyM S McNulty
Jul 1, 1984·Avian Pathology : Journal of the W.V.P.A·J M Sharma, I Tizard
Jul 1, 1999·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·J A StepaniakR S Sundick
Apr 2, 2002·Avian Diseases·Guangxing LiHyun S Lillehoj
Jul 1, 1994·European Journal of Immunology·T W GöbelM D Cooper
Jan 1, 1984·European Journal of Immunology·K N TraillG Wick

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