Avoidance versus use of neuromuscular blocking agents for improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents

The Cochrane Database of Systematic Reviews
Lars H LundstrømJørn Wetterslev

Abstract

Tracheal intubation during induction of general anaesthesia is a vital procedure performed to secure a patient's airway. Several studies have identified difficult tracheal intubation (DTI) or failed tracheal intubation as one of the major contributors to anaesthesia-related mortality and morbidity. Use of neuromuscular blocking agents (NMBA) to facilitate tracheal intubation is a widely accepted practice. However, because of adverse effects, NMBA may be undesirable. Cohort studies have indicated that avoiding NMBA is an independent risk factor for difficult and failed tracheal intubation. However, no systematic review of randomized trials has evaluated conditions for tracheal intubation, possible adverse effects, and postoperative discomfort. To evaluate the effects of avoiding neuromuscular blocking agents (NMBA) versus using NMBA on difficult tracheal intubation (DTI) for adults and adolescents allocated to tracheal intubation with direct laryngoscopy. To look at various outcomes, conduct subgroup and sensitivity analyses, examine the role of bias, and apply trial sequential analysis (TSA) to examine the level of available evidence for this intervention. We searched CENTRAL, MEDLINE, Embase, BIOSIS, International Web of Scien...Continue Reading

References

Jan 1, 1990·Annales Françaises D'anesthèsie Et De Rèanimation·L DominiciP Deligné
Mar 9, 1990·JAMA : the Journal of the American Medical Association·K Dickersin
Jan 1, 1988·Acta Anaesthesiologica Scandinavica·S Helbo-HansenS Trap-Andersen
Jan 1, 1988·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R K BaumgartenH V DeVera
Nov 1, 1984·Anaesthesia·R S Cormack, J Lehane
Jan 1, 1995·Annales Françaises D'anesthèsie Et De Rèanimation·J M RousseauR Pitti
Jan 1, 1995·British Journal of Anaesthesia·S M NimmoH M Robb
Dec 1, 1995·Der Anaesthesist·H W StriebelG Brummer
Jan 1, 1996·Acta Anaesthesiologica Scandinavica·J Viby-MogensenD Ostergaard
Apr 1, 1996·Anaesthesia and Intensive Care·A K Wong, G S Teoh
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Oct 6, 1997·Acta Anaesthesiologica Scandinavica·A Harsten, L Gillberg
Jul 28, 1999·Anesthesiology·H Kirkegaard-NielsenP D Berry
Sep 10, 1999·BMJ : British Medical Journal·S Hollis, F Campbell
Dec 22, 1999·Anesthesiology·K B DominoF W Cheney
Jul 12, 2002·Statistics in Medicine·Julian P T Higgins, Simon G Thompson
Jan 22, 2003·JAMA : the Journal of the American Medical Association·Justin E BekelmanCary P Gross
Jan 25, 2003·BMJ : British Medical Journal·Douglas G Altman, J Martin Bland
Feb 1, 2003·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Thomas LieutaudBertrand Debaene
Apr 30, 2003·Anesthesiology·Thomas MenckeThomas Fuchs-Buder
Sep 6, 2003·BMJ : British Medical Journal·Julian P T HigginsDouglas G Altman
Oct 25, 2003·Anesthesiology·Mohamed NaguibSaleh W Alharby
Apr 30, 2004·Statistics in Medicine·Michael J SweetingPaul C Lambert
Jun 18, 2004·Anaesthesia·J J HendersonUNKNOWN Difficult Airway Society
Aug 19, 2004·Acta Anaesthesiologica Scandinavica·C RosenstockL S Rasmussen
Nov 2, 2004·British Journal of Anaesthesia·A W Woods, S Allam
May 10, 2005·Journal of Clinical Epidemiology·Carrol Gamble, Sally Hollis

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