Axillary Sentinel Lymph Nodes in Breast Cancer: Quantitative Evaluation at Dual-Energy CT

Radiology
Xiang ZhangJun Shen

Abstract

Purpose To evaluate the diagnostic performance of quantitative parameters derived from dual-energy CT for the preoperative diagnosis of metastatic sentinel lymph nodes (SLNs) in participants with breast cancer. Materials and Methods For this prospective study, dual-phase contrast agent-enhanced CT was performed in female participants with breast cancer from June 2015 to December 2017. Quantitative dual-energy CT parameters and morphologic parameters were compared between metastatic and nonmetastatic SLNs. The quantitative parameters were fitted to univariable and multivariable logistic regression models. The diagnostic role of morphologic and quantitative parameters was analyzed by receiver operating characteristic curves and compared by using the McNemar test. Results This study included 193 female participants (mean age, 47.6 years ± 10.1; age range, 22-79 years). Quantitative dual-energy CT parameters including slope of the spectral Hounsfield unit curve (λHu) measured at both arterial and venous phases, normalized iodine concentration at both arterial and venous phase, and normalized effective atomic number at the venous phase were higher in metastatic than in nonmetastatic SLNs (P value range, ≤.001 to .031). Univariable a...Continue Reading

References

May 1, 1991·Journal of Computer Assisted Tomography·D E MarchL Needleman
Nov 15, 2000·CA: a Cancer Journal for Clinicians·E C HsuehA E Giuliano
Apr 25, 2003·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M P SchijvenA C Voogd
Aug 9, 2003·The New England Journal of Medicine·Umberto VeronesiRoberto Gennari
Apr 25, 2006·AJR. American Journal of Roentgenology·Soledad AlvarezJulia Cortés
Dec 8, 2006·European Radiology·Thorsten R C JohnsonChristoph R Becker
Aug 16, 2008·International Journal of Clinical Oncology·Tadahiko ShienTakayuki Kinoshita
Feb 25, 2010·Annals of Surgical Oncology·Stephen B Edge, Carolyn C Compton
May 12, 2010·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Yvette AnderssonLeif Bergkvist
Feb 21, 2013·PloS One·Zilai PanFuhua Yan
Sep 21, 2013·Journal of Computer Assisted Tomography·Ashok SrinivasanSuresh K Mukherji
Oct 11, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Jacob S EcanowJan M Jeske
Apr 26, 2014·Radiology·Daniele MarinRendon C Nelson
Nov 21, 2014·CA: a Cancer Journal for Clinicians·Simona F ShaitelmanJanice N Cormier
Feb 6, 2015·CA: a Cancer Journal for Clinicians·Lindsey A TorreAhmedin Jemal
Aug 21, 2015·JAMA Oncology·Oreste Gentilini, Umberto Veronesi
Jan 27, 2016·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Abigail S CaudleHenry M Kuerer

❮ Previous
Next ❯

Citations

May 28, 2019·The British Journal of Radiology·Rivka KessnerKarin A Herrmann
Jun 11, 2020·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·L WangT Ouyang
Feb 12, 2020·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Wei Huan FangXiao Zhu Lin
Feb 12, 2021·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Xiaoxia WangJiuquan Zhang
Jan 9, 2021·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Xiaoxia WangJiuquan Zhang
Jul 29, 2021·Physics in Medicine and Biology·Buxin ChenXiaochuan Pan
Oct 16, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Chao AnJie Tian

❮ Previous
Next ❯

Related Concepts

Related Feeds

Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

Breast Invasive Carcinoma

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.