Axon guidance: GTPases help axons reach their targets

Current Biology : CB
G Gallo, P C Letourneau

Abstract

During development and regeneration of the nervous system, axons must correctly navigate to their specific targets through a complex molecular environment. Recent work has shed light on how GTPases of the Ras family are involved in transducing extracellular signals into responses that lead to directed neurite outgrowth.

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Axon Guidance

Axon guidance is a complex neural developmental field that investigates mechanisms through which neurons send out axons to reach its target. Here is the latest research in this domain.